Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: A quasiexperimental study
Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: A quasiexperimental study
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DOI：
10.1089/107555303322524535
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发表时间：
2003-10-01
影响因子：
2.6
通讯作者：
Witek-Janusek, L
中科院分区：
文献类型：
--
作者：
Robinson, FP;Mathews, HL;Witek-Janusek, L
目的：本研究的目的是检查为期 8 周的结构化正念减压 (MBSR) 计划对感染人类免疫缺陷病毒 (HIV) 的个体的感知压力、情绪、内分泌功能、免疫力和功能性健康结果的影响。设计：本研究采用准实验、非随机设计。方法：专门招募（非随机）受试者进行干预（MBSR）或对照组。 MBSR 组在测试前和测试后以及对照组的匹配时间收集数据。进行测试以确定组内变化和组间差异。结果：与对照组相比，MBSR 组的自然杀伤细胞活性和数量显着增加。心理、内分泌或功能健康变量没有发现显着的变化或差异。结论：这些结果提供了初步证据，证明 MBSR 可能有助于提高 HIV 感染者的免疫力。
Objectives: The purpose of this study was to examine the effects of a structured, 8-week, Mindfulness-Based Stress Reduction (MBSR) program on perceived stress, mood, endocrine function, immunity, and functional health outcomes in individuals infected with the human immunodeficiency virus (HIV).Design: This study used a quasiexperimental, nonrandomized design.Methods: Subjects were specifically recruited (nonrandom) for intervention (MBSR) or comparison group. Data were collected at pretest and post-test in the MBSR group and at matched times in the comparison group. t Tests where performed to determine within-group changes and between-group differences.Results: Natural killer cell activity and number increased significantly in the MBSR group compared to the comparison group. No significant changes or differences were found for psychological, endocrine, or functional health variables.Conclusions: These results provide tentative evidence that MBSR may assist in improving immunity in individuals infected with HIV.