OBSTRUCTIVE PULMONARY-DISEASE IN RHEUMATOID-ARTHRITIS

OBSTRUCTIVE PULMONARY-DISEASE IN RHEUMATOID-ARTHRITIS
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DOI:
10.1002/art.1780190316
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发表时间:
1976-01-01
影响因子:
--
通讯作者:
MCLEAN, RL
MCLEAN, RL
中科院分区:
其他
文献类型:
--
作者:
COLLINS, RL;TURNER, RA;MCLEAN, RL

文献摘要

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Twenty-six of 43 patients (60.5%) with classic rheumatoid arthritis (RA) participating in a controlled, prospective study had maximal midexpiratory flow rates (MMEFs) suggestive of obstructive pulmonary disease. Cigarette smokers with RA had significantly lower MMEFs than either nonsmokers with RA or smokers with degenerative joint disease. There was an increased prevalence of the Pi phenotypes MS among the RA patients. Interstitial fibrosis, tobacco smoking and protease inhibitor deficiencies were all significant factors in producing airway obstruction in patients with RA.