INTERPRETATION OF SERUM-CALCIUM IN PATIENTS WITH ABNORMAL SERUM-PROTEINS
INTERPRETATION OF SERUM-CALCIUM IN PATIENTS WITH ABNORMAL SERUM-PROTEINS
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DOI：
10.1136/bmj.4.5893.643
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发表时间：
1973-01-01
影响因子：
105.7
通讯作者：
MILNER, JR
中科院分区：
文献类型：
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作者：
PAYNE, RB;LITTLE, AJ;MILNER, JR
该实验室收到的连续两百份用于“肝功能测试”的样本显示出广泛的异常蛋白质浓度。钙浓度与白蛋白密切相关(r = 0·867)，但与总蛋白关系不太密切(r = 0·682)。从钙对白蛋白的回归方程导出了调节钙浓度的简单公式。调整后的钙 = 钙 - 白蛋白 + 4·0，其中钙的单位为 mg/100 ml，白蛋白的单位为 g/100 ml。在进行肝功能检查的 200 份血液样本中，49 份（24·5%）发现钙浓度低，6 份（3%）钙浓度升高。调整后，观测范围的95%限值与本实验室确定的正常范围的95%限值一致。与基于总蛋白或比重的调整不同，对电泳显示高丙种球蛋白血症的 39 个样本中的白蛋白进行调整后，钙浓度正常。
Two hundred consecutive specimens received in this laboratory for “liver function tests” showed a wide range of abnormal protein concentrations. Calcium concentration correlated closely with albumin (r = 0·867) but less closely with total protein (r = 0·682). A simple formula for adjusting calcium concentration was derived from the regression equation of calcium on albumin. Adjusted calcium = calcium - albumin + 4·0, where calcium is in mg/100 ml and albumin in g/100 ml.Low calcium concentrations were found in 49 (24·5%) and raised concentrations in six (3%) of the 200 blood specimens taken for liver function tests. After adjustment, the 95% limits of the observed range were identical with the 95% limits of the normal range determined in this laboratory. Unlike adjustments based on total protein or specific gravity, the adjustment on albumin in 39 specimens which showed hypergammaglobulinaemia on electrophoresis gave normal calcium concentrations.