Epidemiology of oral cancer in Arab countries.
Epidemiology of oral cancer in Arab countries.
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DOI：
10.15537/smj.2016.3.11388
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发表时间：
2016-03
影响因子：
1.6
通讯作者：
El-Metwally A
中科院分区：
文献类型：
--
作者：
Al-Jaber A;Al-Nasser L;El-Metwally A
回顾在阿拉伯国家进行的关于流行病学、危险因素和预后的口腔癌（OC）研究。以计算机为基础的PubMed文献检索检索在阿拉伯世界进行的关于OC流行病学的研究。在筛选排除标准、交叉参考和检索当地期刊后，共纳入19篇文章。八项流行病学研究发现，每十万人中有1.8至2.13人患癌。口腔癌患者多在五、六十岁之间，一些阿拉伯国家的发病率较低。也门45岁以下人群的OC患病率高得惊人。11项研究探讨了卵巢癌的决定因素或预后。行为决定因素，如无烟烟草（Shamma和Qat）和吸烟与OC密切相关。饮酒和太阳辐射被认为是可能的危险因素。受影响最大的部位是舌头、口腔底部和下唇，受影响部位的变化归因于受研究人群的社会文化行为。鳞状细胞癌是最常被发现的癌症，通常患者在诊断时处于晚期（III和IV）。由于缺乏国家癌症登记和基于人群的研究，大多数阿拉伯国家没有关于卵巢癌真实患病率/发病率的确凿证据。
To review the oral cancer (OC) studies that were conducted in Arab countries with regard to epidemiology, risk factors, and prognosis. A computer-based PubMed literature search was performed to retrieve studies conducted in the Arab world on epidemiology of OC. After screening for exclusion criteria, cross-referencing, and searching local journals, a total of 19 articles were included. Eight prevalence studies found an OC prevalence ranging from 1.8 to 2.13 per 100,000 persons. Oral cancer patients were mostly in their fifth to sixth decade of life, and the incidence in younger age was reported in some Arab countries. Yemenis have an alarming high prevalence of OC among people younger than 45 years. Eleven studies explored determinants or prognosis of OC. Behavioral determinants such as smokeless tobacco (Shamma and Qat), and cigarette smoking were strongly associated with OC. Alcohol drinking and solar radiation exposures were cited as possible risk factors. The most affected sites were tongue, floor of the mouth, and lower lip variations in the affected site were attributed to the socio-cultural behavior of the populations under study. Squamous cell carcinoma was the most frequently detected cancer, and usually patients were in late stages (III and IV) at the time of diagnosis. No solid evidence exists regarding the true OC prevalence/incidence in most Arab countries due to the lack of national cancer registries and population-based studies.