Association between HIV and blood pressure in adults and role of body weight as a mediator: Cross-sectional study in Uganda.
Association between HIV and blood pressure in adults and role of body weight as a mediator: Cross-sectional study in Uganda.
复制标题
DOI：
10.1111/jch.13092
复制
发表时间：
2017-11
期刊：
影响因子：
--
通讯作者：
Danaei G
中科院分区：
文献类型：
--
作者：
Okello S;Ueda P;Kanyesigye M;Byaruhanga E;Kiyimba A;Amanyire G;Kintu A;Fawzi WW;Muyindike WR;Danaei G
We sought to describe the association between HIV and blood pressure levels, and determined the extent to which this relationship is mediated by body weight in a cross-sectional study of HIV-infected and HIV-uninfected controls matched by age, gender, and neighborhood. We fit mixed-effects models to determine the association between HIV and BP and amount of effect of HIV on BP mediated through BMI. We analyzed data from 577 HIV-infected and 538 matched HIV-uninfected participants. HIV infection was associated with 3.3 mmHg lower SBP (1.2 to 5.3), 1.5 mmHg lower DBP (0.2 to 2.9), 0.3 m/s lower PWV (0.1 to 0.4), and 30% lower odds of hypertension (10 to 50%). BMI mediated 25% of the association between HIV and SBP. HIV infection was inversely associated with SBP, DBP and pulse-wave velocity. Comprehensive community-based programs to routinely screen for cardiovascular risk factors irrespective of HIV status should be operationalized in HIV-endemic countries.
登录
查看更多内容
影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
7.7
作者：
Dillon DG;Gurdasani D;Riha J;Ekoru K;Asiki G;Mayanja BN;Levitt NS;Crowther NJ;Nyirenda M;Njelekela M;Ramaiya K;Nyan O;Adewole OO;Anastos K;Azzoni L;Boom WH;Compostella C;Dave JA;Dawood H;Erikstrup C;Fourie CM;Friis H;Kruger A;Idoko JA;Longenecker CT;Mbondi S;Mukaya JE;Mutimura E;Ndhlovu CE;Praygod G;Pefura Yone EW;Pujades-Rodriguez M;Range N;Sani MU;Schutte AE;Sliwa K;Tien PC;Vorster EH;Walsh C;Zinyama R;Mashili F;Sobngwi E;Adebamowo C;Kamali A;Seeley J;Young EH;Smeeth L;Motala AA;Kaleebu P;Sandhu MS;African Partnership for Chronic Disease Research (APCDR)
通讯作者：
African Partnership for Chronic Disease Research (APCDR)
DOI：
10.1097/qai.0b013e318251aeb4
发表时间：
2012-06-01
影响因子：
3.6
作者：
Hermans, Sabine M.;Castelnuovo, Barbara;Manabe, Yukari C.
通讯作者：
Manabe, Yukari C.
影响因子：
3.2
作者：
Ikonomidis, Ignatios;Lekakis, John;Kremastinos, Dimitrios Th.
通讯作者：
Kremastinos, Dimitrios Th.
影响因子：
3.7
作者：
Feigl AB;Bloom DE;Danaei G;Pillay D;Salomon JA;Tanser F;Bärnighausen TW
通讯作者：
Bärnighausen TW