Oxygen radical metabolism in vivo: molecular genetic models and assays.

Oxygen radical metabolism in vivo: molecular genetic models and assays.
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体内氧自由基代谢:分子遗传模型和测定。

DOI:
10.1016/0197-4580(94)90080-9
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发表时间:
1994
影响因子:
4.2
通讯作者:
Gandy,S
Gandy,S
中科院分区:
医学2区
文献类型:
--
作者:
Gandy,S

文献摘要

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对AL Friedlich和LL Butcher文章的评论(见记录1996-23617-001),给出了氧自由基代谢与衰老、阿尔茨海默病(AD),特别是大脑β-淀粉样变性的相关数据。本文给出了一个例子,反驳了超氧自由基在β-淀粉样变性和AD发病机制中的重要作用。(PsycINFO数据库记录(c) 2019 APA,版权所有)
Comments on the article by AL Friedlich and LL Butcher (see record 1996-23617-001) presenting data that associate oxygen radical metabolism with aging, Alzheimer's disease (AD), and, specifically, cerebral β-amyloidosis. An example is presented that argues against an important role for superoxide radicals in the pathogenesis of β-amyloidosis and AD.(PsycINFO Database Record (c) 2019 APA, all rights reserved)