Molecular detection of Treponema denticola and Porphyromonas gingivalis in carotid and aortic atheromatous plaques by FISH:: report of two cases
Molecular detection of Treponema denticola and Porphyromonas gingivalis in carotid and aortic atheromatous plaques by FISH:: report of two cases
复制标题
DOI：
10.1099/jmm.0.45845-0
复制
发表时间：
2005-01-01
影响因子：
3
通讯作者：
Cevenini, R
中科院分区：
文献类型：
--
作者：
Cavrini, F;Sambri, V;Cevenini, R
通过PCR和荧光原位杂交（FISH），在两例动脉粥样硬化患者的动脉粥样硬化斑块中发现了齿垢密螺旋体和牙龈卟啉单胞菌。FISH技术的使用表明，这些牙周病微生物可能在动脉粥样硬化病变下的动脉壁内代谢活跃。
Treponema denticola and Porphyromonas gingivalis have been identified in atheromatous plaques of two patients suffering from atherosclerosis by PCR and fluorescence in situ hybridization (FISH). The use of the FISH technique suggested that these periodontopathic micro-organisms might be metabolically active within the wall of arteries, under the atherosclerotic lesion.