Abdominal Obesity and Physical Inactivity Are Associated with Erectile Dysfunction Independent of Body Mass Index

Abdominal Obesity and Physical Inactivity Are Associated with Erectile Dysfunction Independent of Body Mass Index
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DOI:
10.1111/j.1743-6109.2009.01302.x
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发表时间:
2009-07-01
影响因子:
3.5
通讯作者:
Ross, Robert
Ross, Robert
中科院分区:
医学2区
文献类型:
--
作者:
Janiszewski, Peter M.;Janssen, Ian;Ross, Robert

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勃起功能障碍(艾德)在体重指数(BMI)升高的男性中很常见。然而,高腰围(WC)和低水平的体力活动可以预测艾德独立的BMI. Aim. We调查了BMI,WC和体力活动与艾德. Methods之间的独立关系。受试者包括3,941名成年男性(年龄>= 20岁),从2001 - 2004年国家健康和营养检查调查没有前列腺癌的历史。Logistic回归分析用于检查艾德与BMI、WC和体力活动类别相关性的相对几率。主要结果测量。建立的阈值用于将受试者分为三个WC和BMI类别。体力活动水平分为活跃(>= 150分钟/周),中度活跃(30 - 149分钟/周)和非活跃(<30分钟/周)类别。一个单一的调查问题被用来评估存在的艾德. Results.After控制潜在的混杂因素,男性无论是高WC或肥胖的BMI有一个大约50%的高几率有艾德与男性相比,低WC或正常的BMI,分别。此外,中度活跃或不活跃的男性与活跃的男性相比,艾德的几率高出约40 - 60%。当这三个预测因素(WC,BMI和体力活动水平)进入同一逻辑回归模型,高WC和低体力活动水平(中度活跃和不活跃)与更大的艾德几率独立相关,结论:保持WC水平低于102 cm,并达到推荐的中等强度体力活动量,(>= 150分钟/周)与维持适当的勃起功能有关,无论BMI水平如何。这些结果表明,艾德风险的临床筛查应包括WC和体力活动水平的评估,除了BMI。Janiszewski PM,Janssen I,and Ross R.腹部肥胖和缺乏体力活动与勃起功能障碍相关,与体重指数无关。J Sex Med 2009; 6:1990 - 1998.
Introduction.Erectile dysfunction (ED) is common among men with an elevated body mass index (BMI). However, a high waist circumference (WC) and low levels of physical activity may predict ED independently of BMI.Aim.We investigated the independent relationships between BMI, WC, and physical activity with ED.Methods.Subjects consisted of 3,941 adult men (age >= 20 years) with no history of prostate cancer from the 2001-2004 National Health and Nutrition Examination Survey. Logistic regression analyses were used to examine the relative odds of ED association with categories of BMI, WC, and physical activity.Main Outcome Measures.Established thresholds were used to divide subjects into three WC and BMI categories. Physical activity level was divided into active (>= 150 min/week), moderately active (30-149 min/week), and inactive (< 30 min/week) categories. A single survey question was used to assess the presence of ED.Results.After control for potential confounders, men with either a high WC or an obese BMI had an approximately 50% higher odds of having ED compared with men with a low WC or a normal BMI, respectively. Further, moderately active or inactive men had an approximately 40-60% greater odds of ED compared with active men. When all three predictors (WC, BMI, and physical activity level) were entered into the same logistic regression model, both a high WC and low physical activity level (moderately active and inactive) were independently associated with a greater odds of ED, whereas BMI level was not.Conclusion.Maintaining a WC level below 102 cm and achieving the recommended amount of moderate-intensity physical activity (>= 150 min/week) is associated with the maintenance of proper erectile function, regardless of BMI level. These findings suggest that the clinical screening for ED risk should include the assessment of WC and physical activity level in addition to BMI. Janiszewski PM, Janssen I, and Ross R. Abdominal obesity and physical inactivity are associated with erectile dysfunction independent of body mass index. J Sex Med 2009;6:1990-1998.