Obesity
Obesity
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DOI：
10.1146/annurev.clinpsy.2.022305.095249
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发表时间：
2006-01-01
影响因子：
18.4
通讯作者：
Wadden, Thomas A.
中科院分区：
文献类型：
--
作者：
Fabricatore, Anthony N.;Wadden, Thomas A.
肥胖症的患病率正以惊人的速度增长。因此，近年来，对肥胖的病因、合并症和治疗的研究迅速兴起。虽然新的疗法（行为疗法和药理学疗法）已经被开发出来并进行了测试，但在过去 20 年中，通过非手术方法实现的平均体重减轻几乎保持不变。幸运的是，通过这些方法实现的适度体重减轻与肥胖相关健康问题的显着减少有关。通过最强化的可用治疗（即减肥手术），许多患者的合并症得到缓解。本文定义了肥胖并概述了与体重过重相关的疾病状况。审查治疗方案和结果，并确定未来的步骤，包括预防肥胖的努力。最后，对有关肥胖和抑郁之间关系的文献进行了审查。
The prevalence of obesity is growing at an alarming rate. Thus, investigation into the etiology, comorbidities, and treatment of obesity has burgeoned in recent years. While novel therapies-both behavioral and pharmacological-have been developed and tested, the mean weight losses achieved with nonsurgical approaches have remained virtually unchanged over the past 20 years. Fortunately, the modest weight losses achieved with these methods are associated with significant reductions in obesity-related health problems. With the most intensive available treatment (i.e., bariatric surgery), many patients achieve remission of comorbid conditions. This article defines obesity and provides an overview of the disease conditions associated with excess weight. Treatment options and outcomes are reviewed and future steps-including efforts to prevent obesity-are identified. Finally, the literature on the relationship between obesity and depression is examined.