An Expeditious Assembly of 3,4-Benzannulated 8-Oxabicyclo[3.2.1]octane Systems by [2+2+2] Alkyne Cyclotrimerisation: Total Synthesis of (–)-Bruguierol A†
An Expeditious Assembly of 3,4-Benzannulated 8-Oxabicyclo[3.2.1]octane Systems by [2+2+2] Alkyne Cyclotrimerisation: Total Synthesis of (–)-Bruguierol A†
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通过 [2+2+2] 炔环三聚反应快速组装 3,4-苯并环化 8-氧杂双环[3.2.1]辛烷系统：(–)-Bruguierol A† 的全合成
DOI：
10.1002/ejoc.200700648
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发表时间：
2007
影响因子：
2.8
通讯作者：
R. Gonnade
中科院分区：
文献类型：
--
作者：
C. Ramana;Sumanth R. Salian;R. Gonnade
探讨了用交叉炔环三聚反应构建苯- 8-氧杂环[3.2.1]辛烷体系的简便方法。用此方法合成了(-)-bruguierol A，并确定了其绝对构型。（©Wiley-VCH Verlag GmbH & Co. KGaA，德国Weinheim 69451, 2007）
Facile construction of benzene-fused 8-oxabicyclo[3.2.1]octane systems by employing a cross alkyne cyclotrimerisation reaction was explored. With this procedure, (–)-bruguierol A was synthesised, and its absolute configuration was established. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)