Clinical characteristics in patients with ossification of the posterior longitudinal ligament: A prospective multi-institutional cross-sectional study
Clinical characteristics in patients with ossification of the posterior longitudinal ligament: A prospective multi-institutional cross-sectional study
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DOI：
10.1038/s41598-020-62278-3
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发表时间：
2020-03-26
影响因子：
4.6
通讯作者：
Kawaguchi, Yoshiharu
中科院分区：
文献类型：
--
作者：
Hirai, Takashi;Yoshii, Toshitaka;Kawaguchi, Yoshiharu
后纵韧带骨化（OPLL）可发生在整个脊柱，有时可导致脊柱疾病。虽然OPLL患者有时会因为疼痛而出现身体限制，但OPLL患者的疼痛特征及其对日常生活活动（ADL）的影响尚未得到准确评估。因此，我们进行了一项多中心前瞻性研究，以评估颈椎后纵韧带骨化症的症状是否与颈椎病（CS）的症状不同。共入组了263例诊断为颈椎OPLL的患者和50例诊断为CS的患者，并提供了自我报告的结局，包括对日本骨科协会（乔亚）颈椎病评估问卷（JOACMEQ）、乔亚背痛评估问卷（JOABPEQ）、视觉模拟量表（VAS）和SF-36评分的回答。脊髓病的严重程度与JOACMEQ和JOABPEQ的各个领域显着相关。每个领域的VAS评分与乔亚评分之间呈负相关。乔亚评分与SF-36的心理健康、躯体疼痛、躯体功能、情感角色和躯体角色领域之间存在显著正相关。
Ossification of the posterior longitudinal ligament (OPLL) can occur throughout the entire spine and can sometimes lead to spinal disorder. Although patients with OPLL sometimes develop physical limitations because of pain, the characteristics of pain and effects on activities of daily living (ADL) have not been precisely evaluated in OPLL patients. Therefore, we conducted a multi-center prospective study to assess whether the symptoms of cervical OPLL are different from those of cervical spondylosis (CS). A total of 263 patients with a diagnosis of cervical OPLL and 50 patients with a diagnosis of CS were enrolled and provided self-reported outcomes, including responses to the Japanese Orthopaedic Association (JOA) Cervical Myelopathy Evaluation Questionnaire (JOACMEQ), JOA Back Pain Evaluation Questionnaire (JOABPEQ), visual analog scale (VAS), and SF-36 scores. The severity of myelopathy was significantly correlated with each domain of the JOACMEQ and JOABPEQ. There was a negative correlation between the VAS score for each domain and the JOA score. There were significantly positive correlations between the JOA score and the Mental Health, Bodily Pain, Physical Functioning, Role Emotional, and Role Physical domains of the SF-36.