Investigation of dynamic deformation of the midbrain in rear-end collision using human brain FE model
Investigation of dynamic deformation of the midbrain in rear-end collision using human brain FE model
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DOI：
10.1080/10255842.2020.1795142
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发表时间：
2020-07-17
影响因子：
1.6
通讯作者：
Shinoda, Jun
中科院分区：
文献类型：
--
作者：
Atsumi, Noritoshi;Iwamoto, Masami;Shinoda, Jun
轻度创伤性脑损伤（TBI），包括脑震荡，可导致急性和慢性阶段影响身体或认知领域的症状。在这项研究中，我们研究了脑干的动态变形，这可能是重要的这些症状，使用人脑有限元模型，通过重建模拟追尾碰撞在三个不同的速度。在所有的模拟中，高的最大主应变值被观察到在中脑高于胼胝体。这些发现可以为轻度TBI相关的脑部疾病提供一些机械见解。
Mild traumatic brain injury (TBI), including concussions, can cause symptoms affecting physical or cognitive domains in the acute and chronic phases. In this study, we investigated the dynamic deformation of the brain stem, which might be important for these symptoms, using a human brain finite element model through reconstruction simulations of rear-end collisions in three different velocities. In all simulations, high maximum principal strain values were observed at the midbrain that were higher than those in the corpus callosum. These findings could provide some mechanical insights into brain disorders associated with mild TBI.