VACCINATION WITH ANAPLASMA-CENTRALE - RESPONSE AFTER AN EXPERIMENTAL CHALLENGE WITH ANAPLASMA-MARGINALE
VACCINATION WITH ANAPLASMA-CENTRALE - RESPONSE AFTER AN EXPERIMENTAL CHALLENGE WITH ANAPLASMA-MARGINALE
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DOI：
10.1007/bf02297324
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发表时间：
1987-05-01
影响因子：
1.7
通讯作者：
GALLETO, C
中科院分区：
文献类型：
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作者：
ANZIANI, OS;TARABLA, HD;GALLETO, C
用A. centrale和随后的挑战A.边缘进行了评估。将20头14 ~ 16月龄的荷斯坦阉牛分为两组，每组12头和8头（组I和组II）。组I在第0天接种107 A.第二组为对照组。在第125天，两组均用5 × 105的抗病毒药物进行攻击。107 A.边缘感染的红细胞A.中央接种产生低寄生虫血症（最大hivin × 2.7%）、中等细胞压积（PCV）福尔斯下降（最小hivin × 20.5%）和无临床症状。攻毒后，组I的寄生虫血症（最大hivin x 2.3%）和PCV（最小hivin x 20.1%）显著低于组II（分别为7.5%和14.5%）。第二组的四头阉牛发生了急性无形体病，需要治疗。
The haematological and clinical responses to vaccination with A. centrale and to subsequent challenge with A. marginale were evaluated. Twenty Holstein steers 14 to 16 months of age were divided into two groups of 12 and eight animals respectively (groups I and II). Group I was inoculated on day zero with 107 A. centrale-infected erythrocytes and group II was kept as a control. On day 125 both groups were challenged with 5 .times. 107 A. marginale-infected erythrocytes. A. centrale inoculation produced low parasitaemias (maximum .hivin.x 2.7%), moderate packed cell volume (PCV) falls (minimum .hivin.x 20.5%) and no clinical symptoms. After the challenge group I had significantly lower parasitaemia (maximum .hivin.x 2.3%) and higher PCV (minimum .hivin.x 20.1%) than group II (7.5% and 14.5% respectively). Four steers from group II developed acute anaplasmosis and required treatment.