Techniques for observing fetal behavior in utero: a comparison of chemomyelotomy and spinal transection.
Techniques for observing fetal behavior in utero: a comparison of chemomyelotomy and spinal transection.
复制标题
观察子宫内胎儿行为的技术：化疗骨髓切开术和脊柱横断术的比较。
DOI：
10.1002/dev.420170608
复制
发表时间：
1984
影响因子：
2.2
通讯作者：
Robinson,SR
中科院分区：
文献类型：
--
作者：
Smotherman,WP;Richards,LS;Robinson,SR
化学骨髓切开术和脊髓横断术这两种手术已被用来化学阻断或物理切断怀孕大鼠的脊髓，从而无需使用麻醉即可直接观察胎儿的行为。在四个胎龄（第 17、18、19 和 20 天）研究每种手术对胎儿行为的影响。化疗组和脊髓横断组之间的胎儿活动存在显着差异，包括总体活动水平以及行为发育变化模式的差异。这种不同的影响表明，在胎儿行为研究中，化疗和脊髓横断术并不是等效的母体准备。
Two procedures–chemomyelotomy and spinal transection–have been utilized to chemically block or phsycially sever the spinal cord of pregnant rats, enabling direct observation of fetal behavior without the use of anesthesia. The effect of each procedure on fetal behavior was studied at four gestatoinal ages (Days 17, 18, 19, and 20). Substantial differneces in fetal activity were found between chemomyelotomy and spinal transection groups, including differnces in the overall level of activity as well as the pattern of developmental change of behavior. Such differntial effects indicate that chemomyelotomy and spinal transection are not equivalent maternal preparations in the study of fetal behavior.