The ankle brachial index is associated with leg function and physical activity: The walking and leg circulation study
The ankle brachial index is associated with leg function and physical activity: The walking and leg circulation study
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DOI：
10.7326/0003-4819-136-12-200206180-00008
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发表时间：
2002-06-18
影响因子：
39.2
通讯作者：
Clark, E
中科院分区：
文献类型：
--
作者：
McDermott, MM;Greenland, P;Clark, E
背景：踝臂指数（ABI）是下肢缺血的一种无创、可靠的测量方法。目的：探讨踝臂指数（ABI）与下肢功能的关系，设计：横断面研究，地点：芝加哥地区的3个医学中心，参与者：740名男性和女性（460例外周动脉疾病患者）。测量：7天内用加速度计测量身体活动，6分钟步行，4米步行速度，站立平衡和ABI。结果：33%的外周动脉疾病患者有间歇性跛行。ABI低于0.40的参与者中，只有不到40%的人连续步行6分钟，而ABI在1.00至1.50之间的参与者中，这一比例超过95%。与ABI为1.10至1.50相比，ABI小于0.50与6分钟内步行距离较短相关（β回归系数= -523 ft [95%Cl，-592至-454 ft]; P < 0.001），体力活动较少（β = -514.8活动单位[Cl，-657至-373活动单位]; P < 0.001），4米步行速度较慢（β = -0.21 m/s [Cl，-0.27至-0.15 m/s]; P < 0.001），并且保持串联站立10秒的可能性较小（优势比，0.37 [CI，0.18 - 0.76]; P = 0.007），校正典型混杂因素后。ABI和功能之间的关联强于腿部症状和functions.Conclusions之间的关联：ABI，一种非侵入性的测试，可以在医疗办公室进行，是更密切相关的腿部功能的人与外周动脉疾病比间歇性跛行或其他腿部症状。这些数据支持使用ABI来识别下肢功能异常。
Background: The ankle brachial index (ABI) is a noninvasive, reliable measure of lower-extremity ischemia. However, the relationship between ABI and lower-extremity function has not been well studied.Objective: To describe the association between the ABI and lower-extremity function.Design: Cross-sectional study.Setting: 3 academic medical centers in the Chicago area.Participants: 740 men and women (460 with peripheral arterial disease).Measurements: Accelerometer-measured physical activity over 7 days, 6-minute walk, 4-m walking velocity, standing balance, and ABI.Results: 33% of participants with peripheral arterial disease had intermittent claudication. Fewer than 40% of participants with an ABI less than 0.40 walked continuously for 6 minutes compared with more than 95% of participants with an ABI between 1.00 and 1.50. Compared with an ABI of 1.10 to 1.50, an ABI less than 0.50 was associated with shorter distance walked in 6 minutes (beta-regression coefficient = -523 ft [95% Cl, -592 to -454 ft]; P < 0.001), less physical activity (beta = -514.8 activity units [Cl, -657 to -373 activity units]; P < 0.001), slower 4-m walking velocity (beta = -0.21 m/s [Cl, -0.27 to -0.15 m/s]; P < 0.001), and less likelihood of maintaining a tandem stand for 10 seconds (odds ratio, 0.37 [Cl, 0.18 to 0.76]; P = 0.007), after adjustment for typical confounders. Associations between ABI and function were stronger than associations between leg symptoms and function.Conclusions: The ABI, a noninvasive test that can be performed in a medical office, is more closely associated with leg function in persons with peripheral arterial disease than is intermittent claudication or other leg symptoms. These data support the use of the ABI to identify abnormal lower-extremity function.