Progressive prosopagnosia - Clinical and neuroimaging results

Progressive prosopagnosia - Clinical and neuroimaging results
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DOI:
10.1212/01.wnl.0000144347.40132.6a
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发表时间:
2004-11-23
期刊:
影响因子:
9.9
通讯作者:
Poncet, M
Poncet, M
中科院分区:
医学1区
文献类型:
--
作者:
Joubert, S;Felician, O;Poncet, M

文献摘要

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作者报告了一个患者的纵向病例研究与右颞变异额颞叶变性。他的缺陷最初仅限于视觉感知障碍,2年后发展为严重的语义障碍。神经影像学数据表明,潜在的退行性过程,最初仅限于单峰视觉联想皮层,进展沿着腹侧通路的多模态区域负责整合知识从各种形式(前颞叶)。
The authors report the longitudinal case study of a patient with the right temporal variant of frontotemporal lobar degeneration. His deficit, initially limited to visuoperceptual disturbances, progressed 2 years later to a severe semantic breakdown. Neuroimaging data indicate that the underlying degenerative process, initially confined to unimodal visual associative cortices, progressed along the ventral pathways to multimodal areas in charge of integrating knowledge from various modalities ( the anterior temporal lobes).