Near-infrared light-responsive graphene oxide composite multilayer capsules: a novel route for remote controlled drug delivery

Near-infrared light-responsive graphene oxide composite multilayer capsules: a novel route for remote controlled drug delivery
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DOI:
10.1039/c2cc38417e
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发表时间:
2013-01-01
影响因子:
4.9
通讯作者:
Raichur, Ashok M.
Raichur, Ashok M.
中科院分区:
化学2区
文献类型:
--
作者:
Kurapati, Rajendra;Raichur, Ashok M.

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基于氧化石墨烯(GO)独特的光学性质,利用GO复合微胶囊实现药物的近红外(NIR)光控制释放是一种新颖而简单的方法。在NIR激光照射时,由于局部加热,微胶囊以逐点方式破裂,这反过来触发了封装的抗癌药物阿霉素(Dox)从这些胶囊中的光控释放。
A novel and simple route for near-infrared (NIR)-light controlled release of drugs has been demonstrated using graphene oxide (GO) composite microcapsules based on the unique optical properties of GO. Upon NIR-laser irradiation, the microcapsules were ruptured in a point-wise fashion due to local heating which in turn triggers the light-controlled release of the encapsulated anticancer drug doxorubicin (Dox) from these capsules.