Intraindividual comparison of a blue-light filter on visual function: AF-1 (UY) versus AF-1 (UV) intraocular lens
Intraindividual comparison of a blue-light filter on visual function: AF-1 (UY) versus AF-1 (UV) intraocular lens
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DOI：
10.1016/j.jcrs.2007.11.049
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发表时间：
2008-04-01
影响因子：
2.8
通讯作者：
Tetz, Manfred
中科院分区：
文献类型：
--
作者：
Mester, Ulrich;Holz, Frank;Tetz, Manfred
目的：评价AF-1(Uy)带黄色发色团的蓝光滤过型人工晶状体(IOL)对视功能(包括对比视觉和色觉)的影响。地点：德国的5个眼科临床中心。方法：采用前瞻性随机多中心研究和个体内比较的方法，比较了两种类型的人工晶状体，除了1个上有蓝光滤光片外，其他类型的人工晶体都是相同的。术后评估裸眼和最佳矫正视力、瞳孔大小、对比视力(早期治疗糖尿病视网膜病变研究表、功能视力对比测试、明视、中间视、眩光中间视)和颜色辨别(Farnsworth-Munsell 100色调测试、明视和中间视)。结果：除蓝光依赖的色觉外，两种人工晶状体的差异均无统计学意义。在12个月的随访期和6个月以上的明视期，蓝光滤过型人工晶状体的蓝色知觉显著降低。尽管有差异，但所有测量的总误差分数都在正常范围内，没有患者报告色觉受损。结论：带有黄色发色团的蓝光滤过性人工晶状体对对比视力和视力没有影响。然而，蓝色的颜色知觉受损在统计学上是显著的。蓝觉损害未超过正常范围或引起主观色觉障碍。
PURPOSE: To evaluate the effect of the AF-1 (UY) blue-light-filtering intraocular lens (IOL) with a yellow chromophore (Hoya) on visual function, including contrast vision and color perception. SETTINGS: Five clinical ophthalmology centers in Germany.METHODS: Two types of IOLs that were identical except for a blue-light filter on 1 were compared in a prospective randomized multicenter study with intraindividual comparisons. Postoperatively, uncorrected and best corrected visual acuities, pupil size, contrast vision (Early Treatment Diabetic Retinopathy Study chart, functional acuity contrast test, photopic, mesopic, mesopic with glare), and color discrimination (Farnsworth-Munsell 100-hue test, photopic and mesopic) were evaluated.RESULTS: There were no significant differences between the 2 IOLs except in color vision dependent on blue light. Color perception for blue with the blue-light-filtering IOL was significantly reduced under mesopic conditions over the 12-month follow-up and under photopic conditions over 6 months. Despite the difference, all measured total error scores were within normal range and no patient reported impaired color vision.CONCLUSIONS: The blue-light-filtering IOL with a yellow chromophore had no effect on contrast vision and visual acuity. However, the impairment of color perception for blue was statistically significant. The impairment of the blue perception did not exceed the normal range or induce subjective disturbance of color vision.