Partial amino acid sequence analysis of human placenta monoamine oxidase A and bovine liver monoamine oxidase B.
Partial amino acid sequence analysis of human placenta monoamine oxidase A and bovine liver monoamine oxidase B.
复制标题
人胎盘单胺氧化酶A和牛肝单胺氧化酶B的部分氨基酸序列分析。
DOI：
10.1016/s0006-291x(88)80861-1
复制
发表时间：
1988
影响因子：
3.1
通讯作者：
Weyler,W
中科院分区：
文献类型：
--
作者：
Chen,SA;Weyler,W
我们制备了人胎盘单胺氧化酶A型（MAO-A）和牛单胺氧化酶B型（MAO-B）的肽图，并测定了其中21个肽的氨基酸序列。这些序列已与cDNA推导的人MAO-A和-B氨基酸序列进行了比较。特别有趣的结果是鉴定出两组MAO-A肽，它们的序列与从cDNA序列推断出的序列不同。这一观察结果与MAO-A可能由两个亚基组成的观点是一致的，这两个亚基在初级氨基酸序列上相似但不相同。
We have prepared peptide maps from human placenta monoamine oxidase type A (MAO-A) and bovine monoamine oxidase type B (MAO-B) and determined the amino acid sequences of 21 of these peptides. These sequences have been compared to the cDNA deduced amino acid sequences of human MAO-A and -B. A result of special interest is the identification of two sets of MAO-A peptides which have sequences different from those deduced from cDNA sequences. This observation is consistent with the notion that MAO-A may be composed of at two subunits which are similar but not identical in primary amino acid sequence.