Trichomonas Vaginalis Treatment Reduces Vaginal HIV-1 Shedding
Trichomonas Vaginalis Treatment Reduces Vaginal HIV-1 Shedding
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DOI：
10.1097/olq.0b013e318186decf
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发表时间：
2009-01-01
影响因子：
3.1
通讯作者：
Martin, David H.
中科院分区：
文献类型：
--
作者：
Kissinger, Patricia;Amedee, Angela;Martin, David H.
Background: Vaginal HIV-1 shedding has been associated with Trichomonas vaginalis (TV) infection and could play a role in HIV transmission. The purpose of the study was to examine if effective TV treatment reduces the presence of vaginal HIV-1 RNA.Methods: TV+ women attending an HIV outpatient clinic in New Orleans, LA, who resolved infection (n = 58) and TV-negative controls (n = 92). matched on antiretroviral therapy (ART) were examined and interviewed at baseline, 1, and 3 months. TV status was tested by culture and the amount of cell free HIV-1 RNA in the vaginal fluids was determined by the Amplicor HIV-1 Monitor ultrasensitive assay.Results: Most women (81.3%) were black and the mean age was 37.5 (SD 8.7). At baseline, 46.0% had plasma HIV-1 RNA >= 10,000 copies/mL, 26.4% had CD4
