Fifty years of developmental genetics.
Fifty years of developmental genetics.
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发育遗传学五十年。
DOI：
10.1111/j.2164-0947.1983.tb02806.x
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
Gluecksohn-Waelsch,S
中科院分区：
文献类型：
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作者：
Gluecksohn-Waelsch,S
亲爱的莎拉，邀请我为你的荣誉向一个节日捐款，这让我有点恐慌。我知道，如果我要在《学术期刊》上发表一篇原创研究论文，我就不可能达到你的完美标准。当特定酶的纯化和结晶没有包括在实验方案中时，你怎么可能对基因对酶活性的影响的研究留下深刻的印象？因此，我决定远离原始的研究报告，而不是贡献给你的Festschrift一些想法，我在荣誉的LC邓恩的演讲中发展。这堂课讲述的是我所从事的发展遗传奋进领域的思想史，贯穿了几乎半个世纪，在这段时间里，你我相识并成为朋友。所以，那次演讲的大致内容，就是我给你们的论文集的贡献.我记得汉斯·克拉克在我们抵达这个国家后不久就谈到了你，大约在他的赞助下你完成了博士研究。鲁迪·舍恩海默在找博士后助理克拉克给你的推荐信让他印象深刻.接下来我听到的是鲁迪抱怨说，世界上没有什么可以改变你的日常安排，其中包括严格遵守上午晚些时候到达。即使你用同样多的深夜离开实验室来弥补这一点，鲁迪，一个德国学校的产物，很难接受这种不受约束的行为！然而，你们在研究蛋白质代谢方面的合作活动所取得的巨大成功和你们坚定不移的忠诚弥补了你们在军国主义传统方面的不足。我还记得在布朗克斯莎士比亚大道你父母的房子里拜访过你，这是一个以其高标准的传统和好客而闻名的家，这些年来你一直保持并继续保持着这些标准。我永远不会忘记菲茨·莱宁在纽约大学的塞维罗·奥乔亚实验室呆了一段时间后，离开这里前往德国时，你为他举行的告别宴会。我知道他会很高兴为这个节日做贡献。我想引用Heini Waelsch的话来结束这些个人评论，他也很高兴能够为这个Festschrift做出贡献，他做了这样一个经典的评论：“莎拉，我总是知道你什么时候打电话，因为电话铃响得更慢！”莎拉，亲爱的，为了荣誉我们五十年的友谊，我用我的演讲向你致敬，关于五十年的发育遗传学。
The invitation to make a contribution to a Festschrift in your honor, dear Sarah, threw me into a slight panic. I knew that I could not hope to live up to your standards of perfection if I were to offer an original research paper for publication in the Festschrift. How could you possibly be impressed with studies of the effects of genes on enzyme activities when purification and crystallization of the particular enzyme (s) were not included in the experimental protocol? So I decided to stay away from original research reports and instead to contribute to your Festschrift some thoughts developed in a lecture I gave in honor of LC Dunn. This lecture dealt with the history of ideas in my own field of endeavor, that of developmental genetics, throughout the period of almost half a century during which you and I have known each other and been friends. So, the more or less precise text of that lecture is my contribution to your Festschrift. I remember Hans Clarke talking of you soon after our arrival in this country and around the time you completed your doctoral research under his sponsorship. Rudi Schoenheimer was looking for a postdoctoral associate and he was impressed by the recommendation Clarke gave you. The next thing I heard about you was when Rudi complained that nothing in the world could change your daily schedule, which included strict adherence to late morning arrivals. Even though you compensated for this by more than equally late night departures from the lab, it was hard for Rudi, a product of German schools, to accept such unregimented behavior! However, the great successes achieved by your collaborative activities in the study of protein metabolism and your unwavering loyalty made up for your deficiencies in militaristic traditions. I remember visiting you in your parents’ house on Shakespeare Avenue in the Bronx-a home notable for its high standards of tradition and hospitality, standards that you have maintained and continue to do throughout the years. I shall never forget the farewell party you gave for Fitzi Lynen when he left for Germany, after his stay at New York University in the laboratory of Severo Ochoa. I know how happy he would have been to contribute to this Festschrift. I want to end these personal remarks by citing Heini Waelsch, who also would have been very happy to have been able to contribute to this Festschrift, and who made this classical comment:“Sarah, I always know when you are calling because the phone rings more slowly!” Sarah, dear, in honor of our fifty years of friendship I offer my tribute to you with my lecture on fifty years of developmental genetics.