Template Subtraction to Remove CI Stimulation Artifacts in Auditory Steady-State Responses in CI Subjects
Template Subtraction to Remove CI Stimulation Artifacts in Auditory Steady-State Responses in CI Subjects
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DOI：
10.1109/tnsre.2016.2622979
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发表时间：
2017-08-01
影响因子：
4.9
通讯作者：
Moonen, Marc
中科院分区：
文献类型：
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作者：
Deprez, Hanne;Gransier, Robin;Moonen, Marc
目前，基于对受伪影污染的信号部分进行线性插值 (LI)，可以从电诱发稳态响应 (EASSR) 测量中消除人工耳蜗 (CI) 刺激伪影。仅当 CI 刺激伪影短于脉冲间间隔（即，对于对侧通道且刺激脉冲速率高达每秒 500 个脉冲 (pps)）时，LI 才会成功。本文的目的是开发和评估模板减法 (TS) 方法，以消除连续 CI 刺激伪影，以便准确测量 EASSR。模板构建 (TC) 基于包含 CI 刺激伪影但无同步神经反应的 EEG 记录。从感兴趣的记录中减去构建的模板。比较 TS 和 LI 方法以及不同 TC 持续时间的响应幅度和延迟。正如预期的那样，TS 和 LI 后对侧通道的响应幅度和延迟相同。在同侧通道中，只有在 TS 后，响应幅度和延迟才在预期范围内。 TC 持续时间可以从 5 分钟减少到 1 分钟，而不会对响应延迟产生显着影响。 TC 持续时间仅为 1 分钟的 TS 可以消除各个对侧和同侧 EEG 记录通道中的所有 CI 刺激伪影。
Cochlear implant (CI) stimulation artifacts are currently removed from electrically evoked steady-state response (EASSR) measurements based on a linear interpolation (LI) over the artifact- contaminated signal parts. LI is only successful if CI stimulation artifacts are shorter than the interpulse interval, i.e., for contralateral channels and stimulation pulse rates up to 500 pulses per second (pps). The objective of this paper is to develop and evaluate a template subtraction (TS) method to remove continuous CI stimulation artifacts in order to accurately measure EASSRs. The template construction (TC) is based on an EEG recording containing CI stimulation artifacts but no synchronous neural response. The constructed templates are subtracted from the recording of interest. Response amplitudes and latencies are compared for the TS and LI method, and for different TC durations. The response amplitudes and latencies in contralateral channels are the same after TS and LI, as expected. In ipsilateral channels, response amplitudes and latencies are within the expected range only after TS. The TC duration can be reduced from 5 min to 1minwithout a significant effect on response latency. TS with a TC duration of only 1 min allows to remove all CI stimulation artifacts in individual contra-and ipsilateral EEG recording channels.