Single institution results of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of pancreas in 78 patients
Single institution results of radical antegrade modular pancreatosplenectomy for adenocarcinoma of the body and tail of pancreas in 78 patients
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DOI：
10.1002/jhbp.362
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发表时间：
2016-07-01
影响因子：
3
通讯作者：
Strasberg, Steven M.
中科院分区：
文献类型：
--
作者：
Grossman, Julie G.;Fields, Ryan C.;Strasberg, Steven M.
本报告的目的是介绍78例患者的根治性顺行模块化胰脾切除术（RAMPS）的结果。方法78例患者13年内行RAMPS手术。建立了一个处理胰腺腺癌RAMPS的数据库，以便将其转换为一组表格。每个表包含主题的一个元素。该数据库是根据1999年至2013年接受RAMPS手术的患者的临床记录填充的。结果56例患者为前路匝道，22例为后路匝道。94%的标本切线边缘呈阴性。总体R0率为85%。平均淋巴结数20个。没有30天内死亡或住院死亡，但有两名患者在90天内死亡。胰瘘和术后输血是最常见的并发症。中位生存期为24.6个月，5年总精算生存期为25.1%。结论RAMPS技术切缘阴性率高，淋巴结回收效果好。78名患者的长期生存结果可能准确地反映了目前使用这种技术治疗这种肿瘤的可能性。
BackgroundThe purpose of this report is to present results of the radical antegrade modular pancreatosplenectomy (RAMPS) procedure in 78 patients from a single center.MethodsSeventy-eight patients had RAMPS procedure over 13 years. A database dealing with RAMPS for adenocarcinoma of the pancreas was constructed so that it could be converted into a set of tables. Each table covered one element of the subject. The database was populated from clinical records of patients who had a RAMPS procedure from 1999 to 2013.ResultsFifty-six patients had anterior RAMPS and 22 had posterior RAMPS. Negative tangential margins were obtained in 94% of specimens. Overall the R0 rate was 85%. Mean lymph node count was 20. There were no 30-day or in-hospital mortalities but two patients died within 90 days. Pancreatic fistula and need for postoperative transfusion were the most common complications. Median survival was 24.6 months and 5-year overall actuarial survival was 25.1%.ConclusionsThe RAMPS technique resulted in high negative tangential margin rates and good lymph node retrieval. The long-term survival result in 78 patients is probably an accurate reflection of what is possible with this tumor using this technique at this time.