Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report
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DOI:
10.1542/peds.2009-1878c
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发表时间:
2010-01-01
期刊:
影响因子:
8
通讯作者:
Winter, Harland
Winter, Harland
中科院分区:
医学2区
文献类型:
--
作者:
Buie, Timothy;Campbell, Daniel B.;Winter, Harland

文献摘要

被引文献

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自闭症谱系障碍(ASDs)是临床上常见的异质性神经发育障碍。胃肠道疾病和相关症状在asd患者中经常被报道,但关键问题,如这些疾病的患病率和最佳治疗方法,尚不完全清楚。识别和描述asd胃肠道功能障碍的主要困难是许多受影响个体经历的沟通困难。一个多学科小组审查了医学文献,目的是为这一患者群体的胃肠道问题的诊断、评估和管理提供循证建议。该小组的结论是,目前还没有基于证据的建议。专家组的一致意见是,自闭症患者在胃肠道问题的诊断、检查和治疗方面应该得到与非自闭症患者相同的彻底和标准的护理。护理人员应该意识到,自闭症患者的问题行为可能是潜在疾病(包括一些胃肠道疾病)的主要或唯一症状。对于这些患者,行为和医疗护理的整合可能是最有益的。确定了未来研究的重点,以促进我们对asd患者胃肠道疾病的理解和管理。儿科2010;125: S1-S18
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs. Pediatrics 2010; 125: S1-S18