Pharmaceutical availability across levels of care: evidence from facility surveys in Ghana, Kenya, and Uganda.
Pharmaceutical availability across levels of care: evidence from facility surveys in Ghana, Kenya, and Uganda.
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跨护理水平的药物可用性：加纳，肯尼亚和乌干达的设施调查的证据。
DOI：
10.1371/journal.pone.0114762
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Gakidou E
中科院分区：
文献类型：
--
作者：
Masters SH;Burstein R;DeCenso B;Moore K;Haakenstad A;Ikilezi G;Achan J;Osei I;Garshong B;Kisia C;Njuguna P;Babigumira J;Kumar S;Hanlon M;Gakidou E
在这项研究中，我们使用在加纳、肯尼亚和乌干达进行的国家代表性调查中的设施水平数据来了解这三个国家的药品供应情况。2012年，我们进行了一项调查，从每个国家的200多家设施中收集有关药品和其他设施指标的信息。我们分析有关药品可获得性的数据，并量化其与各种设施水平指标的关联。我们既分析了每个国家各种基本药物清单(EML)所界定的基本药物的可获得性，也分析了所有被调查的被认为对治疗各种高负担疾病(包括EML上的疾病)重要的药品的可获得性。我们发现，这三个国家在可获得性方面存在异质性，加纳的可获得性总体上好于乌干达和肯尼亚。为了分析设施层面因素与药品缺货之间的关系，我们使用了一个二项回归模型。我们发现，与缺货相关的因素因国家而异，但在所有国家，设施中实验室的存在和设施中车辆的存在都与减少缺货显著相关。这项研究的结果突显了这三个国家基本药物供应不足的情况，并表明需要采取更多措施来加强供应系统，以保持库存不受干扰。
In this study we use facility-level data from nationally representative surveys conducted in Ghana, Kenya, and Uganda to understand pharmaceutical availability within the three countries. In 2012, we conducted a survey to capture information on pharmaceuticals and other facility indicators from over 200 facilities in each country. We analyze data on the availability of pharmaceuticals and quantify its association with various facility-level indicators. We analyze both availability of essential medicines, as defined by the various essential medicine lists (EMLs) of each respective country, and availability of all surveyed pharmaceuticals deemed important for treatment of various high-burden diseases, including those on the EMLs. We find that there is heterogeneity with respect to availability across the three countries with Ghana generally having better availability than Uganda and Kenya. To analyze the relationship between facility-level factors and pharmaceutical stock-out we use a binomial regression model. We find that the factors associated with stock-out vary by country, but across all countries both presence of a laboratory at the facility and presence of a vehicle at the facility are significantly associated with reduced stock-out. The results of this study highlight the poor availability of essential medicines across these three countries and suggest more needs to be done to strengthen the supply system so that stock remains uninterrupted.
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影响因子：
3.7
作者：
Bazargani YT;Ewen M;de Boer A;Leufkens HG;Mantel-Teeuwisse AK
通讯作者：
Mantel-Teeuwisse AK
影响因子：
168.9
作者：
Lozano, Rafael;Naghavi, Mohsen;Murray, Christopher J. L.
通讯作者：
Murray, Christopher J. L.
DOI：
10.4269/ajtmh.2009.80.737
发表时间：
2009-05-01
影响因子：
3.3
作者：
Kangwana, Beth B.;Njogu, Julius;Snow, Robert W.
通讯作者：
Snow, Robert W.
影响因子：
3.7
作者：
Kaur, Harparkash;Goodman, Catherine;Abdulla, Salim
通讯作者：
Abdulla, Salim
影响因子：
3.7
作者：
Pasquet A;Messou E;Gabillard D;Minga A;Depoulosky A;Deuffic-Burban S;Losina E;Freedberg KA;Danel C;Anglaret X;Yazdanpanah Y
通讯作者：
Yazdanpanah Y