TIPSOTf-Promoted Tandem Reaction through Rearrangement of Epoxides into Aldehydes with Selective Alkyl Migration Followed by the Prins-Type Cyclization to Cyclopentanes
TIPSOTf-Promoted Tandem Reaction through Rearrangement of Epoxides into Aldehydes with Selective Alkyl Migration Followed by the Prins-Type Cyclization to Cyclopentanes
复制标题
TIPSOTf 通过环氧化物重排成醛并选择性烷基迁移促进串联反应，然后进行 Prins 型环化成环戊烷
DOI：
10.1055/s-0031-1290324
复制
发表时间：
2010
期刊：
影响因子：
2
通讯作者：
and Yoshiki Morimoto
中科院分区：
文献类型：
--
作者：
Takeshi Kodama;Shingo Harada;Takeshi Tanaka;Yoshimitsu Tachi;and Yoshiki Morimoto
发现了在硝基甲烷中由 TIPSOTf 促进的三取代环氧化物生成环戊烷的串联反应。它包括环氧化物立体定向重排成醛，伴随选择性烷基迁移以及随后醛类生成环戊烷的普林斯型环化。
The tandem reaction of trisubstituted epoxides to cyclopentanes promoted by TIPSOTf in nitromethane has been found. It consists of stereospecific rearrangement of epoxides into aldehydes accompanied with selective alkyl migration and subsequent Prins-type cyclization of the aldehydes generated to cyclopentanes.