Prognostic importance of the right ventricular function assessed by Doppler tissue imaging.
Prognostic importance of the right ventricular function assessed by Doppler tissue imaging.
复制标题
DOI：
10.1016/s1525-2167(02)00171-3
复制
发表时间：
2003-12-01
期刊：
影响因子：
--
通讯作者：
Krejci, J
中科院分区：
文献类型：
--
作者：
Meluzin, J;Spinarova, L;Krejci, J
目标：我们试图评估是否收缩期和舒张期三尖瓣环的峰值速度作为右心室收缩和舒张功能的指标是预后的重要性，在患者有症状的heartfailure.METHODS和RESULTS：该研究包括139例连续有症状的心力衰竭。他们的平均左心室射血分数为24%（范围，10-39%）;根据纽约心脏协会，107例患者（77%）处于功能III级。所有患者均接受了临床和实验室检查，标准超声心动图完成了三尖瓣环运动的多普勒组织成像，以及右侧心导管插入术。对他们的心脏相关死亡和非致命性心脏事件进行随访，包括需要植入心律转复除颤器和因心力衰竭住院治疗。中位随访时间为11个月（范围：1-48个月）。有17例心脏相关死亡和23例非致死性心脏事件。多变量逐步考克斯回归模型揭示了三个有效的预测生存和无事件生存的因素：心力衰竭病因、左心室舒张末期内径和收缩期三尖瓣环峰值速度（Sa）。Sa组
AIMS: We sought to assess whether the peak systolic and diastolic tricuspid annular velocities as indicators of the right ventricular systolic and diastolic function are of prognostic importance in patients with symptomatic heart failure.METHODS AND RESULTS: The study included 139 consecutive patients with symptomatic heart failure. Their mean left ventricular ejection fraction was 24% (range, 10-39%); 107 patients (77%) were in functional class III according to the New York Heart Association. All patients underwent clinical and laboratory examination, standard echocardiography completed by the Doppler tissue imaging of the tricuspid annular motion, and the right-sided heart catheterization. They were followed up for cardiac-related death and non-fatal cardiac events including the need for implantation of a cardioverter-defibrillator and hospitalization for heart failure. The median follow-up was 11 months (range, 1-48 months). There were 17 cardiac-related deaths and 23 non-fatal cardiac events. The multivariate stepwise Cox regression modelling revealed three effective predictors for both survival and event-free survival: aetiology of heart failure, left ventricular end-diastolic diameter, and the peak systolic tricuspid annular velocity (Sa). Patients with Sa