Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and Gas Vesicles.
Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and Gas Vesicles.
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DOI：
10.1128/genomea.01039-13
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发表时间：
2013-12-12
期刊：
影响因子：
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通讯作者：
Salmond GP
中科院分区：
文献类型：
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作者：
Fineran PC;Iglesias Cans MC;Ramsay JP;Wilf NM;Cossyleon D;McNeil MB;Williamson NR;Monson RE;Becher SA;Stanton JA;Brügger K;Brown SD;Salmond GP
粘质沙雷氏菌（Serratia sp.）菌株ATCC 39006是一种革兰氏阴性菌，属于肠杆菌科，能产生多种具有生物活性的次生代谢产物，包括三吡咯红色素灵菌红素以及β - 内酰胺类抗生素1 - 碳青霉烯 - 2 - 烯 - 3 - 羧酸（一种碳青霉烯类抗生素）。该菌株是已知的肠杆菌科中唯一能天然产生作为漂浮细胞器的气孢囊的成员。在此，我们公布该菌株的基因组序列，它已作为分析抗生素生物合成及调控的模型。
Serratia sp. strain ATCC 39006 is a Gram-negative bacterium and a member of the Enterobacteriaceae that produces various bioactive secondary metabolites, including the tripyrrole red pigment prodigiosin and the β-lactam antibiotic 1-carbapenen-2-em-3-carboxylic acid (a carbapenem). This strain is the only member of the Enterobacteriaceae known to naturally produce gas vesicles, as flotation organelles. Here we present the genome sequence of this strain, which has served as a model for analysis of the biosynthesis and regulation of antibiotic production.