EFFECT OF PREGNANCY AND HORMONAL CHANGES ON THE ACTIVITY OF RHEUMATOID-ARTHRITIS
EFFECT OF PREGNANCY AND HORMONAL CHANGES ON THE ACTIVITY OF RHEUMATOID-ARTHRITIS
复制标题
DOI：
10.3109/03009748309102886
复制
发表时间：
1983-01-01
影响因子：
2.1
通讯作者：
HUSBY, G
中科院分区：
文献类型：
--
作者：
OSTENSEN, M;AUNE, B;HUSBY, G
在31例类风湿关节炎（RA）发病后生育了49名婴儿的患者中，评估了妊娠对类风湿关节炎（RA）活动的影响。75%的患者经历了妊娠相关的RA缓解。分娩后疾病加重的发生率为62%。类风湿关节炎对妊娠和胎儿无不良影响。在月经周期或使用激素避孕药（雌激素、孕激素）期间，激素的变化似乎不会影响类风湿性关节炎的症状。讨论了妊娠期间RA缓解可能涉及的因素。
The effect of pregnancy on the activity of rheumatoid arthritis (RA) was evaluated in 31 patients who had given birth to 49 infants after the onset of their disease. Pregnancy-associated remission of RA was experienced by 75% of the patients. Disease exacerbation after delivery occurred in 62% of them. RA had no harmful effect on pregnancy or on the fetus. Hormonal changes during the menstrual cycle or during the use of hormonal contraceptives [estrogen, progestagen] did not seem to influence the symptoms of RA. Factors possibly involved in remission of RA during pregnancy are discussed.