The specific disease burden of neuropathic pain: Results of a French nationwide survey
The specific disease burden of neuropathic pain: Results of a French nationwide survey
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DOI：
10.1016/j.pain.2011.09.014
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发表时间：
2011-12-01
期刊：
影响因子：
7.4
通讯作者：
Bouhassira, Didier
中科院分区：
文献类型：
--
作者：
Attal, Nadine;Lanteri-Minet, Michel;Bouhassira, Didier
我们报告了第一个全国性的神经性疼痛的影响调查，而不是非神经性疼痛，在法国一般人群的生活质量和医疗保健利用。一份邮政调查问卷被发送给了4554名有代表性的样本，这些样本来自一项对30155名有或没有慢性疼痛的受试者的初步全国调查。它包括疼痛特征（神经性疼痛症状量表，DN4）、生活质量（医疗结果短表12，SF-12）、睡眠、焦虑/抑郁症状（医院焦虑和抑郁量表）和医疗保健利用。共回收问卷3899份（85.6%），可评估问卷3816份（97.9%），确认疼痛状态的问卷3165份（82.9%）。根据DN4报告疼痛和神经性特征的受试者在与生活质量和睡眠相关的所有维度上表现出更高程度的损害，并且比报告无神经性特征的疼痛和无疼痛的疼痛的受试者有更高的焦虑/抑郁评分（P < 0.01）。他们还更多地利用卫生保健设施，特别是在神经治疗和神经科医生就诊方面（21%比9%；P < 0.01）。多变量分析显示，疼痛的神经性特征对生活质量损害有独立贡献（SF-12的身体和精神评分分别为P < 0.0001和P = 0.0005）。我们的研究表明，慢性疼痛的疾病负担取决于疼痛的性质，独立于其强度和持续时间。(C) 2011年国际疼痛研究协会。Elsevier b.v.版权所有。
We report the first nationwide survey of the impact of neuropathic pain, as opposed to nonneuropathic pain, on quality of life and health care utilization in the French general population. A postal questionnaire was sent to a representative sample of 4554 respondents from an initial nationwide survey of 30,155 subjects with or without chronic pain. It included pain characteristics (Neuropathic Pain Symptom Inventory, DN4), quality of life (Medical Outcomes Short Form 12, SF-12), sleep, anxiety/depressive symptoms (Hospital Anxiety and Depression Scale) and health care utilization. In total, 3899 (85.6%) questionnaires were returned, 3816 (97.9%) could be assessed and 3165 subjects (82.9%) confirmed their pain status. Subjects reporting pain and neuropathic characteristics based on the DN4 displayed a higher degree of impairment of all dimensions relating to quality of life and sleep and had higher anxiety/depression scores than those reporting pain without neuropathic characteristics and those without pain (P < .01). They also made greater use of health care facilities, particularly as concerned neurological treatments and visits to neurologists (21% vs 9%; P < .01). Multivariate analyses showed that the neuropathic characteristics of pain made an independent contribution to quality-of-life impairment (P < .0001 and P = .0005 for the physical and mental scores of the SF-12 respectively). Our study indicates that the disease burden of chronic pain depends on the nature of the pain, independently of its intensity and duration. (C) 2011 International Association for the Study of Pain. Published by Elsevier B. V. All rights reserved.