Chlamydia pneumoniae strain TWAR, Mycoplasma pneumoniae, and viral infections in acute respiratory disease in a university student health clinic population.
Chlamydia pneumoniae strain TWAR, Mycoplasma pneumoniae, and viral infections in acute respiratory disease in a university student health clinic population.
复制标题
肺炎衣原体菌株 TWAR、肺炎支原体以及大学生健康诊所人群中急性呼吸道疾病的病毒感染。
DOI：
10.1093/oxfordjournals.aje.a115654
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发表时间：
1990
影响因子：
5
通讯作者：
Altman,J
中科院分区：
文献类型：
--
作者：
Thom,DH;Grayston,JT;Wang,SP;Kuo,CC;Altman,J
Clinical and serologic data were collected on 667 University of Washington students who presented to the David Hall Student Health Center between 1983 and 1987 with acute respiratory disease. Sera were tested for evidence of acute or past infections withChlamydia pneumoniaestrain TWAR,Chlamydia trachomatis,Mycoplasma pneumoniae, influenza A virus, influenza B virus, adenovirus, and respiratory syncytial virus. Pharyngeal swab specimens were cultured forC. pneumoniaeandC. trachomatls, but not for the other agents. Evidence of acute infection withC. pneumoniaewas found in 20 patients and evidence of an acute infection withM. pneumoniaein 29 patients.C. pneumoniaewas associated with 9% andM. pneumoniaewith 11% of 149 pneumonias diagnosed clinically, and with 20% and 22%, respectively, of the 59 pneumonias confirmed on chest radiograph. There was no evidence of seasonality inC. pneumoniaeorM. pneumoniaeinfections. Compared with patients with M. pneumoniae, patients withC. pneumoniaewere less likely to have a temperature greater than 37.8°C (10% vs. 34%), but were more likely to present with a sore throat (80% vs. 52%) or hoarseness (30% vs. 3%). The mean number of days from onset of symptoms until enrollment was longer in patients withC. pneumoniaeinfections than in those withM. pneumoniae(12.8 vs. 7.9 days), or those with a viral infection (12.8 vs. 7.3 days), suggesting a more gradual onset of disease caused byC. pneumoniae.
