Clinical outcome of peripheral nerve decompression in diabetic and nondiabetic peripheral neuropathy
Clinical outcome of peripheral nerve decompression in diabetic and nondiabetic peripheral neuropathy
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DOI：
10.1097/01.sap.0000221979.13847.30
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发表时间：
2006-10-01
影响因子：
1.5
通讯作者：
Agaoglu, Galip
中科院分区：
文献类型：
--
作者：
Siemionow, Maria;Alghoul, Mohammed;Agaoglu, Galip
据报道，糖尿病患者的周围神经减压术可恢复感觉和改善功能。在这项研究中，回顾性分析了12例糖尿病和20例非糖尿病下肢周围神经病变患者接受手术减压。术前、术后6个月、术后9 ~ 15个月进行Tinel试验、肌力检查和2分辨别力临床评价。根据症状改善和功能恢复，将临床结局分为优秀、良好或一般。32例患者接受了36次手术。共行下肢神经减压术99例。小脚趾（P = 0.008）和大脚趾（P = 0.038）的肌肉功能（P <0.001）和2分辨别力有统计学显著改善。在平均7.7个月时，90%的患者显示疼痛和功能显著改善。结论是，手术减压与糖尿病和特发性神经病变患者的临床结局显著改善相关，有叠加压迫的证据。
Surgical decompression of peripheral nerves in patients with diabetes was reported to restore sensation and improve function. In this study, a retrospective review of 12 diabetic and 20 nondiabetic patients with lower-extremity peripheral neuropathy who underwent surgical decompression was performed. Clinical evaluation by Tinel test, muscle power examination, and 2-point discrimination were performed preoperatively, at 6 months, and between 9 and 15 months postdecompression. Clinical outcomes were classified into excellent, good, or fair based on improvement in symptoms and return of function. Thirty-two patients underwent 36 surgeries. in which 99 lower-extremity nerves were decompressed. There was a statistically significant improvement in muscle function (P < 0.001) and 2-point discrimination for the small toe (P = 0.008) and big toe (P = 0.038). At a mean of 7.7 months, 90% of patients showed significant improvement in pain and function. It is concluded that surgical decompression was associated with significant improvement in clinical outcome in patients with diabetic and idiopathic neuropathy with evidence of superimposed compression.