Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network
Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network
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DOI：
10.1016/j.jad.2018.12.099
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发表时间：
2019-03-01
影响因子：
6.6
通讯作者：
Jones, Lisa
中科院分区：
文献类型：
--
作者：
Gordon-Smith, Katherine;Saunders, Kate;Jones, Lisa
背景：电子纵向情绪监测已被证明可以为临床环境中的情感障碍患者所接受，但其在大规模研究中的应用尚未建立。方法：通过邮寄和电子邮件邀请，我们邀请了 4080 名过去患有情感障碍的研究参与者，他们在 10 年的时间里被招募到双相情感障碍研究网络 (BDRN)，参与在线每周情绪监测。此外，自 2015 年 1 月起，我们邀请所有新招募的 BDRN 研究参与者在被招募到 BDRN 时参与情绪监测。结果：过去的参与者中在线情绪监测的采用率为 20%，迄今为止新参与者中的这一比例为 46%，其中去年招募的参与者最有可能注册 (61%)。超过 90% 的情绪监测参与者参与至少一个月，平均参与时间超过一年（58 周），最大参与时间超过三年（165 周）。过去和新的 BDRN 参与者提供至少 4 周（分别为 91%、92%）、3 个月（78%、82%）、6 个月（65%、54%）或一年（51%、44%）数据的比例没有显着差异。局限性：我们招募参与者进行电子前瞻性情绪监测的经验可能不一定完全适用于与我们描述的情况截然不同的研究情况。结论：大规模用于研究目的的情感障碍电子纵向情绪监测是可行的，新招募的参与者中采用率最高。
Background: Electronic longitudinal mood monitoring has been shown to be acceptable to patients with affective disorders within clinical settings, but its use in large-scale research has not yet been established.Methods: Using both postal and email invitations, we invited 4080 past research participants with affective disorders who were recruited into the Bipolar Disorder Research Network (BDRN) over a 10 year period to participate in online weekly mood monitoring. In addition, since January 2015 we have invited all newly recruited BDRN research participants to participate in mood monitoring at the point they were recruited into BDRN.Results: Online mood monitoring uptake among past participants was 20%, and among new participants to date was 46% with participants recruited over the last year most likely to register (61%). More than 90% mood monitoring participants engaged for at least one month, with mean engagement period greater than one year (58 weeks) and maximum engagement for longer than three years (165 weeks). There were no significant differences in the proportion of past and new BDRN participants providing data for at least 4 weeks (91%, 92% respectively), 3 months (78%, 82%), 6 months (65%, 54%) or one year (51%, 44%).Limitations: Our experiences with recruiting participants for electronic prospective mood monitoring may not necessarily generalise fully to research situations that are very different from those we describe.Conclusions: Large-scale electronic longitudinal mood monitoring in affective disorders for research purposes is feasible with uptake highest among newly recruited participants.