The development of the 'quality-of-life for respiratory illness questionnaire (QOL-RIQ)': A disease-specific quality-of-life questionnaire for patients with mild to moderate chronic non-specific lung disease
The development of the 'quality-of-life for respiratory illness questionnaire (QOL-RIQ)': A disease-specific quality-of-life questionnaire for patients with mild to moderate chronic non-specific lung disease
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DOI：
10.1016/s0954-6111(97)90034-2
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发表时间：
1997-05-01
影响因子：
4.3
通讯作者：
Kaptein, AA
中科院分区：
文献类型：
--
作者：
Maille, AR;Koning, CJM;Kaptein, AA
慢性非特异性肺病（CNSLD）包括哮喘和慢性阻塞性肺病（COPD）。最近，在医疗保健领域，人们越来越关注患者健康的功能、心理和社会方面;他们的生活质量（QOL）。针对CNSLD患者的生活质量研究在很长一段时间内一直相当不发达。然而，最近，生活质量的重要性越来越被认识到，一些研究小组已经开始研究生活质量在CNSLD患者在更详细的。本文介绍了一种疾病特异性生活质量量表的建设，为轻度至中度严重的CNSLD患者。列出了与生活质量几个领域有关的项目，并询问了171名全科医生中的CNSLD患者，每个项目的问题有多大（采用7分制Likert量表进行评估）。应用项目选择程序后，构建了一个一维QOL问卷，包括55个项目，分为7个领域的分量表：呼吸问题，身体问题，情绪，情况触发或增强呼吸问题，一般活动，日常和家庭活动，社会活动，关系和性。构式问卷的领域分量表的可靠性估计值在0.68至0.89之间变化，呼吸系统疾病QOL问卷（QOL-RIQ）总量表的可靠性估计值为0.92。通过调查QOL领域分量表与疾病严重程度的几个指标之间的关系，以及疾病严重程度变量、背景特征和症状对QOL的相对贡献，使用回归分析，获得了问卷结构效度的第一印象。目前正在进行进一步的研究，以便在更大程度上验证调查表（结构效度、重测信度和对变化的反应）。
Chronic non-specific lung disease (CNSLD) encompasses asthma as well as chronic obstructive pulmonary disease (COPD). Recently in health care, there has been increasing awareness in the functional, psychological and social aspects of the health of patients; their quality of life (QOL). Quality-of-life research addressing CNSLD patients has been rather underdeveloped for a long period of time. Recently, however, the importance of QOL is being increasingly recognized, and several research groups have started to study QOL in CNSLD patients in more detail.This paper describes the construction of a disease-specific QOL instrument for patients with mild to moderately severe CNSLD. Items relating to several domains of QOL were listed, and 171 CNSLD patients in general practice were asked, how much of a problem each item had been (assessed on a seven-point Likert scale). After applying an item-selection procedure, a uni-dimensional QOL questionnaire was constructed consisting of 55 items divided into seven domain subscales: breathing problems, physical problems, emotions, situations triggering or enhancing breathing problems, general activities, daily and domestic activities, and social activities, relationships and sexuality. Reliability estimates of the domain subscales of the constructed questionnaire varied from 0.68 to 0.89, and was 0.92 for the QOL for Respiratory Illness Questionnaire (QOL-RIQ) total scale. A first impression of the construct validity of the questionnaire was gained by investigation of the relationship between the QOL domain subscales and several indicators of illness severity, as well as the relative contribution of illness severity variables, background characteristics and symptoms to QOL, using regression analysis. Further research to validate the questionnaire to a greater extent (construct validity, test-retest reliability and responsiveness to change) is currently taking place.