Abstract representations of location and facing direction in the human brain.
Abstract representations of location and facing direction in the human brain.
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DOI：
10.1523/jneurosci.3873-12.2013
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发表时间：
2013-04-03
期刊：
影响因子：
--
通讯作者：
Epstein RA
中科院分区：
文献类型：
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作者：
Vass LK;Epstein RA
人类和其他移动的生物一样，依靠空间表征来引导从一个地方到另一个地方的导航。虽然以前的工作已经确定了参与寻路的神经系统，这些系统所支持的特定空间代码还没有得到很好的理解。我们使用功能性磁共振成像（fMRI）来识别人类内侧颞叶和内侧顶叶内编码两个基本空间量的区域-位置和面向方向-以一种从感官输入中抽象出来的方式。大学生们在观看在几个熟悉的校园地点拍摄的照片时被扫描。多体素模式分析表明，左前下托，压后复合体（RSC），顶枕沟（POS）编码的位置身份，即使在非重叠的意见，而右前下托编码面向方向，即使在非连续的位置。这些区域支持的位置和方向代码可能对我们在扩展环境中导航和理解其大规模空间结构的能力至关重要。
Humans, like other mobile organisms, rely on spatial representations to guide navigation from place to place. Although previous work has identified neural systems involved in wayfinding, the specific spatial codes supported by these systems are not well understood. We use functional magnetic resonance imaging (fMRI) to identify regions within the human medial temporal and medial parietal lobes that encode two fundamental spatial quantities – location and facing direction – in a manner that abstracts away from sensory inputs. University students were scanned while viewing photographs taken at several familiar campus locations. Multivoxel pattern analyses indicated that the left presubiculum, retrosplenial complex (RSC), and parietal-occipital sulcus (POS) coded location identity even across non-overlapping views, whereas the right presubiculum coded facing direction even across non-contiguous locations. The location and direction codes supported by these regions may be critical to our ability to navigate within the extended environment and to understand its large-scale spatial structure.