Toward a conceptual framework of the acceptability of tuberculosis treatment in children using a theory generative approach.
Toward a conceptual framework of the acceptability of tuberculosis treatment in children using a theory generative approach.
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DOI：
10.1371/journal.pgph.0001267
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Hoddinott, Graeme
中科院分区：
文献类型：
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作者：
Wademan, Dillon T;Palmer, Megan;Purchase, Susan;van der Zalm, Marieke M;Osman, Muhammad;Garcia-Prats, Anthony J;Seddon, James A;Schaaf, H Simon;Hesseling, Anneke C;Reis, Ria;Reynolds, Lindsey J;Hoddinott, Graeme
描述一个早期整体框架，以评估影响儿童结核病治疗整体可接受性的因素。我们利用理论生成方法开发了一个概念框架。这些领域是通过对现有定义的审查和对儿童结核病治疗可接受性研究中现有定性数据的分析而制定的。领域定义的清晰度是通过研究团队之间的迭代细化实现的。确定了三个领域，每个领域包括几个维度，以全面评估治疗可接受性：(1)可用性，这涉及治疗使用的要求与护理人员和儿童将结核病治疗纳入其日常生活的能力之间的一致性；(2)接受性，描述最终用户对治疗及其实际使用的看法和期望；(3)整合性，描述现有卫生服务与护理人员/儿童利用这些服务的能力之间的关系。我们的框架解决了目前研究中的空白，这些空白没有考虑到照顾者和儿童的情况对结核病治疗的接受和总体可接受性的影响。这种方法可能支持制定更标准、更全面的措施，以改善儿童结核病治疗的提供和经验以及未来的研究。
To describe an early-stage holistic framework towards evaluating factors that impact the overall acceptability of TB treatment along the TB care cascade in children. We developed a conceptual framework utilising a theory generative approach. Domains were developed through review of existing definitions and analysis of existing qualitative data undertaken in acceptability studies of TB treatment in children. Clarity of domain definitions was achieved through iterative refinement among the research team. Three domains, each comprising several dimensions, were identified to holistically evaluate treatment acceptability: (1) usability, which involves the alignment between the requirements of treatment use and caregivers’ and children’s ability to integrate TB treatment into their everyday routines, (2) receptivity, which describes the end-user’s perception and expectations of treatment and its actual use, and (3) integration, which describes the relationship between available health services and caregivers/children’s capacity to make use of those services. Our framework addresses the gaps in current research which do not account for the influence of caregivers’ and children’s contexts on TB treatment uptake and overall acceptability. This approach may support the development of more standard, holistic measures to improve TB treatment delivery and experiences and future research in children.