Are subjective cognitive complaints a risk factor for dementia?
Are subjective cognitive complaints a risk factor for dementia?
复制标题
DOI：
10.1007/s10072-010-0224-6
复制
发表时间：
2010-06-01
影响因子：
3.3
通讯作者：
Sambati, Luisa
中科院分区：
文献类型：
--
作者：
Gallassi, Roberto;Oppi, Federico;Sambati, Luisa
目的是评估4年随访期间主观认知主诉（SCC）患者的预后。对92名SCC患者进行了一项前瞻性研究，调查他们的认知，情感和行为方面。SCC患者分为无客观认知功能障碍（NOCI）、轻度认知功能障碍（MCI）或MCI亚型。结果：NOCI 43例，MCI 49例。在随访期间，45.5%的NOCI患者保持不变，13.9%被诊断为MCI，只有1例进展为痴呆。MCI患者中，32.3%保持稳定，18.4%变为痴呆，4%恢复为NOCI。视觉注意力、行为记忆、长期言语记忆、冷漠和照顾者痛苦是痴呆进展的独立预测因素。
The objective is to evaluate the prognosis of subjective cognitive complaints (SCC) patients during 4-year follow-up. A prospective study on 92 SCC patients investigating their cognitive, affective and behavioural aspects. SCC patients were classified as having no objective cognitive impairment (NOCI), mild cognitive impairment (MCI), or subtypes of MCI. Results: 43 patients were found to have NOCI and 49 MCI. During the follow-up, 45.5% of NOCI patients remained unchanged, 13.9% were diagnosed as MCI and only one progressed to dementia. Of the MCI patients, 32.3% remained stable, 18.4% became demented and 4% reverted to NOCI. Visual attention, behavioural memory, long-term verbal memory, apathy and caregiver distress, provided independent predictors of progression to dementia.