Estimation of fusiform intracranial aneurysm growth by serial magnetic resonance imaging.
Estimation of fusiform intracranial aneurysm growth by serial magnetic resonance imaging.
复制标题
通过系列磁共振成像估计梭形颅内动脉瘤的生长。
DOI：
10.1002/jmri.20944
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
Martin,AlastairJ
中科院分区：
文献类型：
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作者：
Dispensa,BradleyP;Saloner,DavidA;Acevedo-Bolton,Gabriel;Achrol,AchalS;Jou,Lianger-der;McCulloch,CharlesE;Johnston,SClaiborne;Higashida,RandallT;Dowd,ChristopherF;Halbach,VanV;Ko,NerissaU;Lawton,MichaelT;Martin,AlastairJ
PurposeIntracranial aneurysm (IA) growth is associated with increased morbidity. We sought to establish a quantitative computational method based on contrast‐enhanced MR angiography (CE‐MRA) for estimating aneurysmal volume changes over time.Materials and MethodsComputational volume calculations were tested against a distensible phantom. Untreated patients with IA were followed longitudinally with annual MRI. Maximal linear dimensions along the longitudinal axis and two transverse axes were determined by visual review of maximum intensity projection (MIP) data, and aneurysm volume was approximated as (length × width × height)/2. Averages of the visual approximations were compared to the lumenal volume as determined with a computational algorithm using the MRI data.ResultsMRI‐based measurements accurately represented volume changes in the phantom (R2= 0.97, Y = 1.06x + 271 CM3). In the clinical study there were a total of 11 intervals of one‐year follow‐up in six patients (mean ± SD, age = 53 ± 20 years). The raw one‐year growth using the computational volume was 9% ± 17%. The corresponding value for the averaged measurement of the reviewers was 8% ± 14%. Neither the mean values nor the SDs were different (P= .51).ConclusionMRI‐based measurement of aneurysm volume appears feasible for longitudinal studies of aneurysm natural history. J. Magn. Reson. Imaging 2007;26:177–183. © 2007 Wiley‐Liss, Inc.
