Cost study of dermal substitutes and topical negative pressure in the surgical treatment of burns
Cost study of dermal substitutes and topical negative pressure in the surgical treatment of burns
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DOI：
10.1016/j.burns.2013.08.025
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发表时间：
2014-05-01
期刊：
影响因子：
2.7
通讯作者：
Middelkoop, Esther
中科院分区：
文献类型：
--
作者：
Hop, M. Jenda;Bloemen, Monica C. T.;Middelkoop, Esther
背景资料：最近进行的一项随机对照试验研究了真皮替代物（DS）和劈裂皮移植物（SSG）联合局部负压（TNP）在烧伤创面手术治疗中的临床有效性。在目前的研究中，医疗和非医疗费用进行了调查，全面评估这种新的treatment.Methods的好处：主要结果是平均总成本的四种治疗策略：SSG与或不与DS，与或不TNP。从社会角度研究了成本。结果：86例患者被纳入本研究。术后12个月，在用DS和TNP治疗的瘢痕中测得最高弹性（p = 0.027）。DS和TNP治疗的初始成本价格为2912美元，而SSG单独治疗的初始成本价格为1703美元（p < 0.001）。然而，每例患者的平均总成本在两组之间没有显著差异（范围（原文如此）29 097 -（原文如此）43 774）。讨论：介入治疗的成本占总成本的最大7%，总成本在组内和组间变化很大，但没有显著差异。因此，在选择最佳手术干预类型时，成本因素不应起重要作用。(C)2013 Elsevier Ltd和ISBI。All rights reserved.
Background: A recently performed randomised controlled trial investigated the clinical effectiveness of dermal substitutes (DS) and split skin grafts (SSG) in combination with topical negative pressure (TNP) in the surgical treatment of burn wounds. In the current study, medical and non-medical costs were investigated, to comprehensively assess the benefits of this new treatment.Methods: The primary outcome was mean total costs of the four treatment strategies: SSG with or without DS, and with or without TNP. Costs were studied from a societal perspective. Findings were evaluated in light of the clinical effects on scar elasticity.Results: Eighty-six patients were included. Twelve months post-operatively, highest elasticity was measured in scars treated with DS and TNP (p = 0.027). The initial cost price of treatment with DS and TNP was (sic)2912 compared to treatment with SSG alone (sic)1703 (p < 0.001). However, mean total costs per patient did not differ significantly between groups (range (sic)29 097 -(sic)43 774).Discussion: Costs of the interventional treatment contributed maximal 7% to the total costs and total costs varied widely within and between groups, but were not significantly different. Therefore, in the selection of the most optimal type of surgical intervention, cost considerations should not play an important role. (C) 2013 Elsevier Ltd and ISBI. All rights reserved.