Management of intraventricular hemorrhage.
Management of intraventricular hemorrhage.
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DOI：
10.1007/s11910-010-0086-6
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发表时间：
2010-03
影响因子：
5.6
通讯作者：
Ziai, Wendy C.
中科院分区：
文献类型：
--
作者：
Hinson, Holly E.;Hanley, Daniel F.;Ziai, Wendy C.
脑出血是最致命的中风形式，在所有中风亚型中发病率最高。脑室内出血（IVH）是一个预后特别差的体征，预期死亡率在50%至80%之间。IVH是发病率和死亡率的一个重要和独立的贡献者，但针对改善脑室内血栓的治疗一直受到限制。常规治疗的重点是控制高血压和颅内压，同时纠正凝血功能障碍，避免再出血和脑积水等并发症。单纯手术治疗并不能显著改变疾病的自然病程。然而，纤维蛋白溶解结合脑室外引流显示出作为一种减少脑室内血凝块体积和管理IVH并发症的技术的前景。
Brain hemorrhage is the most fatal form of stroke and has the highest morbidity of any stroke subtype. Intraventricular extension of hemorrhage (IVH) is a particularly poor prognostic sign, with expected mortality between 50% and 80%. IVH is a significant and independent contributor to morbidity and mortality, yet therapy directed at ameliorating intraventricular clot has been limited. Conventional therapy centers on managing hypertension and intracranial pressure while correcting coagulopathy and avoiding complications such as rebleeding and hydrocephalus. Surgical therapy alone has not changed the natural history of the disease significantly. However, fibrinolysis in combination with extraventricular drainage shows promise as a technique to reduce intraventricular clot volume and to manage the concomitant complications of IVH.
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