Vesicoureteral reflux in adult women with uncomplicated acute pyelonephritis
Vesicoureteral reflux in adult women with uncomplicated acute pyelonephritis
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DOI：
10.1016/j.urology.2005.01.034
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发表时间：
2005-07-01
期刊：
影响因子：
2.1
通讯作者：
Kim, JH
中科院分区：
文献类型：
--
作者：
Choi, YD;Yang, WJ;Kim, JH
目标.目的探讨膀胱输尿管反流（VUR）在成人单纯性急性肾盂肾炎中的意义。1998年4月至2003年10月，对86例无并发症的急性肾盂肾炎成年女性进行了研究。他们的泌尿道结构没有异常。患者的平均年龄为36.2岁（范围：19 - 54岁）。我们将这些患者分为两组。在第一组（31例患者），我们进行了排尿膀胱尿道造影（VCUG）的第三天的治疗，以证明在急性感染期可能短暂的低度VUR。在第二组（其余55例患者）中，我们在治疗第七天后进行VCUG。86例无并发症的急性肾盂肾炎中仅2例发生VUR（2.3%）。I组无VUR发生，II组2例出现II级返流。这些结果表明，与儿童不同，VUR不是导致成人女性发生急性肾盂肾炎的上行感染的重要因素。关于成年人群中上行感染的病理生理学，需要进一步研究。
Objectives. To evaluate the significance of vesicoureteral reflux (VUR) in adult women with uncomplicated acute pyelonephritis.Methods. Eighty-six adult women with uncomplicated acute pyelonephritis were studied from April 1998 to October 2003. They showed no structural urinary tract abnormalities. The mean age of patients was 36.2 years (range, 19 to 54 years). We divided these patients into two groups. In group I (31 patients), we performed a voiding cystourethrogram (VCUG) on the third day of treatment to demonstrate possible transient low-grade VUR during the acute infectious phase. In group II (the remaining 55 patients), we performed VCUG after the seventh day of treatment.Results. There were only 2 (2.3%) cases of VUR among 86 patients with uncomplicated acute pyelonephritis. No VUR was found in group I, and grade II reflux was found in 2 patients of group II.Conclusions. These results indicate that, unlike in children, VUR is not a significant factor causing ascending infection leading to the development of acute pyelonephritis in adult women. Further research is warranted regarding the pathophysiology of ascending infection in the adult population.