Early Discontinuation of Buprenorphine Therapy for Opioid Use Disorder Among Privately Insured Adults
Early Discontinuation of Buprenorphine Therapy for Opioid Use Disorder Among Privately Insured Adults
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DOI：
10.1176/appi.ps.201900309
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发表时间：
2020-08-01
影响因子：
3.8
通讯作者：
Rosenheck, Robert
中科院分区：
文献类型：
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作者：
Agbese, Edeanya;Leslie, Douglas L.;Rosenheck, Robert
目的：研究丁丙诺啡开始治疗前后早期停止治疗与医疗费用的时间关系。方法：采用MarketScan商业索赔软件，对2013年因阿片类药物使用障碍而开始使用丁丙诺啡并在随后12个月内持续投保的患者(N=6,444)，检验丁丙诺啡开始治疗前后的治疗保留与医疗费用之间的关系。使用协方差分析和广义线性模型(具有伽玛分布/对数链接)比较四个丁丙诺啡保留组(0-3、3-6、6-12和12个月或更长)的费用。结果：丁丙诺啡开始使用前3个月的平均总医疗费用从最短保留组的7,588美元到保留最长组的4,929美元不等(p
Objective: This study examined the temporal relationship between early discontinuation of buprenorphine treatment and health care expenditures before and after treatment initiation.Methods: MarketScan commercial claims for patients who initiated buprenorphine for opioid use disorder in 2013 and had continuous insurance for the subsequent 12 months (N=6,444) were used to examine the relationship between treatment retention and health care expenditures before and after buprenorphine initiation. Analysis of covariance and generalized linear models (with gamma distribution/log link) were used to compare expenditures across four buprenorphine-retention groups (0-3, 3-6, 6-12, and 12 or more months).Results: Average total health care expenditures in the 3 months prior to buprenorphine initiation ranged from a high of $7,588 among those with the shortest retention to $4,929 among those with the longest retention (p