Hepatitis B Virus (HBV) screening strategy to ensure the safety of blood for transfusion through a combination of immunological testing and nucleic acid amplification testing - Japanese experience
Hepatitis B Virus (HBV) screening strategy to ensure the safety of blood for transfusion through a combination of immunological testing and nucleic acid amplification testing - Japanese experience
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DOI：
10.1016/s1386-6532(06)80010-7
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发表时间：
2006-05-01
影响因子：
8.8
通讯作者：
Yoshizawa, Hiroshi
中科院分区：
文献类型：
--
作者：
Yugi, Hisao;Mizui, Masaaki;Yoshizawa, Hiroshi
本文比较了日本B型肝炎病毒（HBV）筛查系统不同组成部分的有效性，该系统包括HBsAg、抗HBc和微量混合液HBV-NAT（核酸扩增技术）检测。HBV DNA阳性的捐助者的特点，和急性HBV感染的自然过程进行了描述。探讨了进一步提高血液安全性的可行性。
This paper compares the efficacy of the different components of the hepatitis B virus (HBV) screening system in Japan, which consists of a combination of HBsAg, anti-HBc and minipool HBV-NAT (nucleic acid amplification technique) testing. The characteristics of HBV DNA-positive donors, and the natural course of acute HBV infection are described. The feasibility of further improvement of blood safety is discussed.