Functional-lesion investigation of developmental stuttering with positron emission tomography
Functional-lesion investigation of developmental stuttering with positron emission tomography
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DOI：
10.1044/jshr.3906.1208
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发表时间：
1996-12-01
期刊：
影响因子：
--
通讯作者：
Cotton, J
中科院分区：
文献类型：
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作者：
Ingham, RJ;Fox, PT;Cotton, J
正电子发射断层扫描（PET）（H2O）-O-15测量静息状态下29名右利手男性的局部脑血流量（CBF），其中10人口吃，19人没有。通过对74个感兴趣区域（ROI）进行采样（每个半球37个）来分析PET图像。在生理学和解剖学上引导ROI放置。生理感兴趣区的位置是基于语音运动激活。通过参考立体定向神经外科图谱定位解剖ROI，并通过cc配准磁共振图像（MRI）确认和微调位置。对于所有受试者，PET和MR图像均正常。非常显著（p
Positron emission tomographic (PET) (H2O)-O-15 measurements of resting-slate regional cerebral blood flow (CBF) were obtained in 29 right-handed men, 10 of whom stuttered and 19 of whom did not. PET images were analyzed by sampling 74 regions of interest (ROIs), 37 per hemisphere. ROI placement was guided both physiologically and anatomically. Physiological ROI placement was based on speech motor activations. Anatomical ROIs were positioned by reference to a stereotactic, neurosurgical atlas with positions confirmed and finely adjusted by cc-registered magnetic-resonance images (MRIs). For all subjects, PET and MR images were normal to visual inspection. Highly significant (p