Prematurity: Infection as an Etiologic Factor
Prematurity: Infection as an Etiologic Factor
复制标题
早产：感染作为病因
作者：
H. Minkoff
早产在围产期死亡率和发病率中占很大比例。大量的证据表明，围产期感染可能在胎膜早破和早产中发挥病因作用。患者阴道植物群和她的局部防御机制（羊水和宫颈粘液的抗菌活性）之间的相互作用可能有助于确定谁是早产。证据牵连感染作为一个原因的劳动审查，并确定可能负责的生物体。潜在的调查和干预的途径概述，这将划定感染在早产中的作用，并导致预防感染引起的早产的一种手段。
Preterm delivery accounts for a substantial percentage of perinatal mortality and morbidity. A large body of evidence suggests that perinatal infections may play an etiologic role in preterm rupture of membranes and preterm labor. The interaction between a patient's vaginal flora and her local defense mechanisms (antibacterial activity of amniotic fluid and cervical mucus) may help determine who delivers prematurely. The evidence implicating infection as a cause of labor is reviewed, and the organisms which may be responsible are identified. Potential avenues of investigation and intervention are outlined which would delineate the role of infections in preterm delivery and lead to a means of preventing some preterm deliveries caused by infection.