Disentangling genetic, environmental, and rater effects on internalizing and externalizing problem behavior in 10-year-old twins

Disentangling genetic, environmental, and rater effects on internalizing and externalizing problem behavior in 10-year-old twins
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DOI:
10.1375/136905204323016140
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发表时间:
2004-04-01
期刊:
TWIN RESEARCH
影响因子:
--
通讯作者:
van den Oord, EJCG
van den Oord, EJCG
中科院分区:
其他
文献类型:
--
作者:
Bartels, M;Boomsma, DI;van den Oord, EJCG

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以往的研究强调了在研究儿童内在化和外在化问题变异的病因学中更大问题的重要性。早期的研究结果表明,父母之间只有适度的共识,并假设父母评估了孩子行为的一个特定方面。在年龄较小的儿童的可比样本中,可加性遗传效应是解释内化和外化行为的个体差异的主要因素。目前尚不清楚这种更大的影响模式和方差分解是否会在年龄较大的儿童中保持一致。儿童行为检查表(Achenbach, 1991),由父母双方完成,收集了2956对10岁的荷兰双胞胎样本。内化综合征和外化综合征的个体差异的病因学使用一个模型进行了检查,该模型纠正了可能的偏倚、特异性效应和不可靠性。最佳拟合模型表明,父母之间的分歧不仅仅是不可靠和/或更大的偏见的结果,而且每个父母也从他/她自己的角度提供了关于孩子行为的具体信息。加性遗传因素、共有环境因素和独特环境因素对内化综合征和外化综合征均有显著影响。
Previous studies have emphasized the importance of rater issues in studying the etiology of variation in internalizing and externalizing problems in children. Earlier results indicate only moderate agreement between parents, and assume that parents assess a specific aspect of their child's behavior. In comparable samples of younger children, additive genetic effects are the main factor explaining individual differences in both internalizing and externalizing behavior. It is unknown whether this pattern of rater influences and variance decomposition will be consistent in older children. Child Behavior Checklists (Achenbach, 1991), completed by both parents, were collected in a sample of 2956 Dutch 10-year-old twin pairs. The etiology of individual differences in internalizing and externalizing syndromes was examined using a model that corrected for possible rater bias, rater-specific effects and unreliability. The best fitting model suggested that disagreement between the parents is not merely the result of unreliability and/or rater bias, but each parent also provides specific information from his/her own perspective on the child's behavior. Significant influences of additive genetic, shared environmental and unique environmental factors were found for internalizing and externalizing syndromes.