The development of search filters for adverse effects of medical devices in medline and embase
The development of search filters for adverse effects of medical devices in medline and embase
复制标题
medline 和 embase 中医疗器械不良反应搜索过滤器的开发
DOI：
10.1111/hir.12260
复制
发表时间：
2019
影响因子：
3.8
通讯作者：
Y. Loke
中科院分区：
文献类型：
--
作者：
S. Golder;K. Farrah;M. Mierzwinski;Kath Wright;Y. Loke
背景目前已经开发出了针对手术中药物不良反应和并发症的客观衍生搜索过滤器，但尚未开发出针对医疗器械不良反应的搜索过滤器。目的开发并验证检索过滤器，用于检索医疗器械不良反应证据。方法从Epistemonikos和卫生技术评估（hta）数据库中进行系统评价。这些综述中报告医疗器械不良反应的纳入研究被随机分为三个测试组和一个验证组记录。利用一个测试集的词频分析，我们构建了一个灵敏度最大化的搜索策略。使用另外两个测试集对该策略进行了改进，然后进行了验证。结果在186篇符合纳入标准的系统综述中，medline收录了1984篇独特的纳入研究，embase收录了1986篇。在medline和embase中搜索通用不良反应的灵敏度分别为84%和83%。然而，当添加特定的不良反应术语时，召回率提高到90%以上。结论：我们推导并验证了新的搜索过滤器，可以检索medline和embase中80%以上的医疗器械不良反应数据记录。需要增加具体的不利影响条款，以达到更高的灵敏度。
Abstract Background Objectively derived search filters for adverse drug effects and complications in surgery have been developed but not for medical device adverse effects. Objective To develop and validate search filters to retrieve evidence on medical device adverse effects from ovid medline and embase. Methods We identified systematic reviews from Epistemonikos and the Health Technology Assessment (hta) database. Included studies within these reviews that reported on medical device adverse effects were randomly divided into three test sets and one validation set of records. Using word frequency analysis from one test set, we constructed a sensitivity maximising search strategy. This strategy was refined using two other test sets, then validated. Results From 186 systematic reviews which met our inclusion criteria, 1984 unique included studies were available from medline and 1986 from embase. Generic adverse effects searches in medline and embase achieved 84% and 83% sensitivity. Recall was improved to over 90%, however, when specific adverse effects terms were added. Conclusion We have derived and validated novel search filters that retrieve over 80% of records with medical device adverse effects data in medline and embase. The addition of specific adverse effects terms is required to achieve higher levels of sensitivity.