OPERATING CHARACTERISTICS OF A BANK CORRELATION TEST FOR PUBLICATION BIAS
OPERATING CHARACTERISTICS OF A BANK CORRELATION TEST FOR PUBLICATION BIAS
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DOI：
10.2307/2533446
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发表时间：
1994-12-01
期刊：
影响因子：
1.9
通讯作者：
MAZUMDAR, M
中科院分区：
文献类型：
--
作者：
BEGG, CB;MAZUMDAR, M
提出了一种调整秩相关检验方法，用于识别Meta分析中的发表偏倚，并通过模拟评估了其操作特性。检验统计量是流行的“漏斗图”的直接统计模拟。荟萃分析中的成分研究的数量、选择机制的性质、效应量估计的方差范围以及真实的潜在效应量都被观察到对确定检验的功效有影响。该检验对于包含75项成分研究的大型荟萃分析具有相当强的效力，但对于包含25项成分研究的荟萃分析仅具有中等效力。然而，在许多具有低功效的配置中，汇总效应量估计值的偏倚也相对较小。尽管如此，在小型荟萃分析中必须谨慎解释该检验。特别是，如果检验不显着，则不能排除偏差。所提出的技术具有潜在的实用性，作为一个探索性的工具，元分析，作为一个正式的程序，以补充漏斗图。
An adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations. The test statistic is a direct statistical analogue of the popular ''funnel-graph.'' The number of component studies in the meta-analysis, the nature of the selection mechanism, the range of variances of the effect size estimates, and the true underlying effect size are all observed to be influential in determining the power of the test. The test is fairly powerful for large meta-analyses with 75 component studies, but has only moderate power for meta-analyses with 25 component studies. However, in many of the configurations in which there is low power, there is also relatively little bias in the summary effect size estimate. Nonetheless, the test must be interpreted with caution in small meta-analyses. In particular, bias cannot be ruled out if the test is not significant. The proposed technique has potential utility as an exploratory tool for meta-analysts, as a formal procedure to complement the funnel-graph.