DEPRESSED CONCENTRATIONS OF OXYTOCIN AND CORTISOL IN CHILDREN WITH RECURRENT ABDOMINAL-PAIN OF NONORGANIC ORIGIN
DEPRESSED CONCENTRATIONS OF OXYTOCIN AND CORTISOL IN CHILDREN WITH RECURRENT ABDOMINAL-PAIN OF NONORGANIC ORIGIN
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DOI：
10.1111/j.1651-2227.1994.tb12989.x
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发表时间：
1994-10-01
期刊：
影响因子：
3.8
通讯作者：
UVNASMOBERG, K
中科院分区：
文献类型：
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作者：
ALFVEN, G;DELATORRE, B;UVNASMOBERG, K
本研究的目的是测量患有非器质性复发性腹痛（RAP）的儿童中催产素、皮质醇和催乳素的血浆浓度。年龄和性别相匹配的 40 名 RAP 儿童和 34 名对照儿童参与了这项研究。禁食过夜后收集血样并进行临床检查。通过放射免疫分析（RIA）测定催产素、皮质醇和催乳素水平。研究发现，与对照组相比，RAP 儿童的催产素和皮质醇浓度显着降低（催产素分别约为 24 和 63 pmol/l，皮质醇分别约为 160 和 300 nmol/l）。三个月后的第二次检查时，催产素和皮质醇水平仍然较低。 IAP 和对照组之间的催乳素水平没有观察到显着差异。
The purpose of the present study was to measure plasma concentrations of oxytocin, cortisol and prolactin in children with recurrent abdominal pain of non-organic origin (RAP). Forty children with RAP and 34 controls, matched for age and sex, participated in the study. A blood sample was collected after an overnight fast in association with clinical examinations. Oxytocin, cortisol and prolactin levels were determined by radioimmunoassay (RIA). Oxytocin and cortisol concentrations in the children with RAP were found to be significantly reduced compared with those of the controls (approximately 24 versus 63 pmol/l for oxytocin and 160 versus 300 nmol/l for cortisol, respectively). The low oxytocin and cortisol levels persisted at a second examination 3 months later. No significant differences in the prolactin levels were observed between IAP and controls.