Numerical study of particle chains of a large number of randomly distributed DEP particles using iterative dipole moment method

Numerical study of particle chains of a large number of randomly distributed DEP particles using iterative dipole moment method
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DOI:
10.1002/jctb.4700
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发表时间:
2016-04-01
影响因子:
3.4
通讯作者:
Wu, Jiankang
Wu, Jiankang
中科院分区:
工程技术4区
文献类型:
--
作者:
Liu, Le;Xie, Chuanchuan;Wu, Jiankang

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介电电泳(DEP)技术已广泛应用于微流控系统中对生物微粒的操纵。大量稠密粒子的DEP相互作用的计算一直是一个具有挑战性的问题。麦克斯韦应力张量(MST)方法在理论上对DEP力具有严格的精度,但其复杂的数值计算却很难实现。本文提出了一种计算均匀电场中大量稠密粒子间相互作用力和粒子链的迭代偶极矩方法(IDM),并通过十粒子相互作用的数值算例,验证了IDM计算粒子间相互作用力的精度与MST方法的一致性。用IDM方法模拟了均匀电场中由50个随机分布的稠密粒子组成的粒子链,并与实验结果进行了比较。不同颗粒尺寸的颗粒链也investigated.CONCLUSIONThe DEP粒子的相互作用力的IDM方法计算的发现是在良好的协议与那些使用麦克斯韦应力张量(MST)方法和易于实现。模拟粒子链的基本特征与实验观察一致。(c)2015年化学工业协会
BACKGROUNDDielectrophoresis (DEP) has widely been used to manipulate bio-particles in microfluidic system. The calculation of DEP interaction of a large number of dense particles has been a challenging issue. The Maxwell stress tensor (MST) method is strictly accurate in theory for DEP forces, but the complicated numerical computation is very difficult to implement. An iterative dipole moment method (IDM) is proposed in this paper to study the interaction forces and particle chains of a large number of dense particles in a uniform electrical field.RESULTSThe numerical example of ten particles interaction confirms that the IDM is able to calculate particle interaction forces in good agreement with the MST method. Particle chains of fifty randomly distributed dense particles in a uniform electrical field were simulated using the IDM method and were well consistent with experimental observations. Particle chains of different particle sizes are also investigated.CONCLUSIONThe interaction forces of DEP particles calculated by the IDM method are found to be in good agreement with those obtained using the Maxwell stress tensor (MST) method and easy to implement. The simulated particle chains show essential characteristics well consistent with experimental observations. (c) 2015 Society of Chemical Industry